A Rare Case and Atypical Metastatic Regions, Pulmonary Giant Cell Carcinoma
PDF
Cite
Share
Request
Interesting Image
P: 74-76
February 2023

A Rare Case and Atypical Metastatic Regions, Pulmonary Giant Cell Carcinoma

Mol Imaging Radionucl Ther 2023;32(1):74-76
1. Akdeniz University Hospital, Department of Nuclear Medicine, Antalya, Turkey
No information available.
No information available
Received Date: 01.10.2021
Accepted Date: 28.01.2022
Publish Date: 23.02.2023
PDF
Cite
Share
Request

ABSTRACT

Sixty two years old man referred to our clinic due to suspicion of thymic mass. The hypermetabolic nodular lesion in the right lung upper lobe was seen in 18F-fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT) in addition to the mass in the anterior mediastinum which was found to without malignancy. The patient underwent wedge resection and final diagnosis was pulmonary giant cell carcinoma. In follow-up 18F-FDG PET/CT multiple lesions with pathological activity were observed in the cerebrum, right postauricular region, bilateral adrenal, stomach, pancreas, pelvic soft tissue, mesenteric, left femur and bilateral lung parenchyma 6 months after. The pathology results of the right frontal, pelvic mass and the postauricular region were metastasis.

Keywords:
Primary pulmonary giant cell carcinoma, 18F-FDG PET/CT, atypical metastasis

References

1
Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JHM, Beasley MB, Chirieac LR, Dacic S, Duhig E, Flieder DB, Geisinger K, Hirsch FR, Ishikawa Y, Kerr KM, Noguchi M, Pelosi G, Powell CA, Tsao MS, Wistuba I; WHO Panel. The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification. J Thorac Oncol 2015;10:1243-1260.
2
Pabón-Carrasco S, Vallejo-Benitez AM, Pabón-Carrasco M, Rodriguez-Zarco E. Primary pulmonary giant cell tumor. Arch Bronconeumol (Engl Ed) 2019;55:60-62.
3
Alasio TM, Sun W, Yang GC. Giant cell carcinoma of the lung impact of diagnosis and review of cytological features. Diagn Cytopathol 2007;35:555-559.
4
Fishback NF, Travis WD, Moran CA, Guinee DG Jr, McCarthy WF, Koss MN. Pleomorphic (spindle/giant cell) carcinoma of the lung. A clinicopathologic correlation of 78 cases. Cancer 1994;73:2936-2945.
5
Baldovini C, Rossi G, Ciarrocchi A. Approaches to tumor classification in pulmonary sarcomatoid carcinoma. Lung Cancer (Auckl) 2019;10:131-149.
6
Plowman RS, Nguyen BD. Primary pulmonary giant cell tumor: (18)F-FDG PET/CT imaging. Rev Esp Med Nucl Imagen Mol 2016;35:274-276.
7
Seo JB, Im JG, Goo JM, Chung MJ, Kim MY. Atypical pulmonary metastases: spectrum of radiologic findings. Radiographics 2001;21:403-417.
8
Hayashi S, Kitada M, Ishibashi K, Matsuda Y, Miyokawa N. Combined large cell neuroendocrine carcinoma with giant cell carcinoma of the lungs: a case report. World J Surg Oncol 2013;11:205.