The Role of a Bone SPECT/CT Scan in the Follow-up of a Solitary Bone Lesion in a Patient with Langerhans’ Cell Histiocytosis
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P: 187-189
October 2021

The Role of a Bone SPECT/CT Scan in the Follow-up of a Solitary Bone Lesion in a Patient with Langerhans’ Cell Histiocytosis

Mol Imaging Radionucl Ther 2021;30(3):187-189
1. Marmara University Pendik Training and Research Hospital, Clinic of Nuclear Medicine, İstanbul, Turkey
No information available.
No information available
Received Date: 28.04.2020
Accepted Date: 29.06.2020
Publish Date: 15.10.2021
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ABSTRACT

Langerhans’ cell histiocytosis (LCH) is a rare disease observed in childhood characterized by the proliferation of Langerhans’ cells resulting in focal or systemic manifestations (including the bones). Here, we present a pediatric case with a localized biopsy-proven LCH, who underwent progression from solitary to multifocal form detected on bone scintigraphy and single photon emission computerized tomography/computed tomography (SPECT/CT) performed within four months. Emphasizing on localized bone pain (predictive of osseous LCH) and local tenderness and swelling usually guides the nuclear physician to perform additional SPECT/CT with presumably an improvement of the diagnostic accuracy as demonstrated in our case.

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