ABSTRACT
Neuroendocrine tumors are slow-growing tumors originating from neuroendocrine cells and capable of metastasis. Most of them are found in the gastrointestinal tract; however, they can also be rarely seen in other organs. Testicular neuroendocrine tumors account for less than 1% of all testicular neoplasms. They may present as primary testicular or secondary tumors from extratesticular sources. Jejunal neuroendocrine tumor metastasis to the testis is extremely rare. We present the case of a 61-year-old man with a jejunal neuroendocrine tumor and metastases to bilateral testicles revealed on Gallium-68-DOTATATE positron emission tomography/computed tomography.
References
1
Antoniadou F, Korkolis D, Koufopoulos N, Manatakis D, Sakellariou S. A well differentiated neuroendocrine tumor of the jejunum with peritoneal carcinomatosis: a case report. Mol Clin Oncol 2018;9:651-655.
2
Landerholm K, Falkmer S, Järhult J. Epidemiology of small bowel carcinoids in a defined population. World J Surg 2010;34:1500-1505.
3
Bodei L, Ambrosini V, Herrmann K, Modlin I. Current Concepts in 68Ga-DOTATATE imaging of neuroendocrine neoplasms: interpretation, biodistribution, dosimetry, and molecular strategies. J Nucl Med 2017;58:1718-1726.
4
Amine MM, Mohamed B, Mourad H, Majed H, Slim C, Mehdi B, Hela M, Nouri R, Rim K, Tahya B, Nabil MM. Neuroendocrine testicular tumors: a systematic review and meta-analysis. Curr Urol 2017;10:15-25.
5
Wang WP, Guo C, Berney DM, Ulbright TM, Hansel DE, Shen R, Ali T, Epstein JI. Primary carcinoid tumors of the testis: a clinicopathologic study of 29 cases. Am J Surg Pathol 2010;34:519-524.
6
Manna S, Narayana SM, Premalata CS. Primary neuroendocrine tumor of the testis masquerading as germ cell tumor – a case report. Eur J Med Health Science 2020;2:518.
7
Fucs M, Romero FR, Germanos de Castro M, de Carvalho Fernandes R, Camara-Lopes LH, Cardenuto Perez MD. Testicular metastasis 10 years after resection of appendiceal carcinoid. Urology 2005;65:591.
8
Danikas D, Sachs R, Dressner RM, Arvanitis ML. Testicular metastasis from ileal carcinoid: report of a case. Dis Colon Rectum 2001;44:1365-1366.
9
Lau HY, Lai V. Metastatic testicular carcinoid tumour. Hong Kong J Radiol 2013;16:69-73.
10
Berdjis CC, Mostofi FK. Carcinoid tumors of the testis. J Urol 1977;118:777-782.
11
Stroosma OB, Delaere KP. Carcinoid tumours of the testis. BJU Int 2008;101:1101-1105.
12
Cope Z. Metastasis of an argentaffin carcinoma in the testicle. British Journal Urol 1930;2:268-272.
13
Blumberg JM, Sedberry S, Kazmi SO. Bilateral asynchronous metastatic carcinoid tumor of the testis. Urology 2005;65:174.