E-ISSN: 2147-1959
Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with <sup>18</sup>F-FDG PET/CT
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VOLUME: 30 ISSUE: 2
P: 126-128
June 2021

Systemic Sarcoidosis Induced by Chemotherapy, Mimicking Metastatic Testicular Carcinoma with 18F-FDG PET/CT

Mol Imaging Radionucl Ther 2021;30(2):126-128
DOI: 10.4274/mirt.galenos.2020.51422
Esra Arslan 1
Tamer Aksoy 1
Süheyla Ekemen 2
Tevfik Fikret Çermik 1
1. University of Health Sciences Turkey, İstanbul Training and Research Hospital, Clinic of Nuclear Medicine, İstanbul, Turkey
2. Bahçeşehir University Faculty of Medicine, Department of Pathology, İstanbul, Turkey
No information available.
No information available
Received Date: 10.11.2019
Accepted Date: 13.06.2020
Publish Date: 03.06.2021
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ABSTRACT

Biopsy of the lytic lesion in the iliac bone revealed granulomatous inflammation suggestive of sarcoidosis. Systemic prednisone at 20-40 mg/daily was started. 18F-FDG PET/CT images showed complete metabolic response to prednisone 8 months following the start of treatment.

A 34-year-old male patient who had left orchiectomy and received three cycles of chemotherapy for testicular mix germ cell carcinoma was referred for 18fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for complaints of weight loss and fever. PET/CT showed multiple and progressive 18F-FDG uptakes in supra and infra diaphragmatic lymphatic regions, and multiple abnormal 18F-FDG uptakes were noted in the lytic formed skeletal lesions. Clinicians remain in doubt regarding the multiple metastatic lesions without elevated serum tumor marker levels (alpha-fetoprotein, beta-human chorionic gonadotrophin, CA19-9, and carcinoembryonic antigen).

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