E-ISSN: 2147-1959
Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT
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VOLUME: 28 ISSUE: 2
P: 83-85
June 2019

Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT

Mol Imaging Radionucl Ther 2019;28(2):83-85
DOI: 10.4274/mirt.galenos.2018.38039
Fevziye Canbaz 1
Murat Aydın 2
Bilge Can Meydan 3
Meltem Ceyhan Bilgici 4
Ender Arıtürk 5
1. Ondokuz Mayıs University Hospital, Department of Nuclear Medicine, Samsun, Turkey
2. Ondokuz Mayıs University Hospital, Department of Pediatric Endocrinology, Samsun, Turkey
3. Ondokuz Mayıs University Hospital, Department of Pathology, Samsun, Turkey
4. Ondokuz Mayıs University Hospital, Department of Pediatric Radiology, Samsun, Turkey
5. Ondokuz Mayıs University Hospital, Department of Pediatric Surgery, Samsun, Turkey
No information available.
No information available
Received Date: 22.09.2018
Accepted Date: 04.11.2018
Publish Date: 24.06.2019
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ABSTRACT

“Nesidioblastosis”, later renamed as “persistent hyperinsulinemic hypoglycemia of infancy” presents as either focal or diffuse neo-differentiation of pancreatic Langerhans islet cells from the ductal epithelium. Differentiation of focal disease from diffuse involvement is crucial for optimal disease management. The current methods used to differentiate the two forms pre-operatively are invasive techniques. The definite role of imaging modalities to differentiate diffuse versus focal form has not yet been proven. Herein, we report a 15 day-old infant having diffuse nesidioblastosis, successfully demonstrated by Ga-68 DOTATATE positron emission tomography/computed tomography imaging that was histopathologically confirmed.

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