ABSTRACT
A 40-year-old woman with a palpable mass lesion in her right breast suggested as breast cancer was admitted to 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) unit for the metabolic characterization of the lesion and for the staging of the disease. The patient had no fever and no evidence of weight loss or night sweats. 18F-FDG PET/CT revealed an isolated solid mass lesion with increased 18F-FDG uptake in the upper outer quadrant of the right breast and increased 18F-FDG uptake in the lymph nodes of the right axilla suspected as primary breast cancer and its local lymph node metastasis. There was no other pathological 18F-FDG uptake in the whole body. Excisional biopsy histopathology revealed diffuse large B-cell non-Hodgkin lymphoma.
Keywords:
Breast, non-Hodgkin lymphoma, PET/CT, 18F-FDG
References
1Woo OH, Yong HS, Shin BK, Park CM, Kang EY. Synchronous bilateral primary breast lymphoma: MRI and pathologic findings. Breast J 2007;13:429-430.
2Lim H, Cho KR, Kim I, Hwang KW, Seo BK, Woo OH, Oh YW, Bae JW. Primary Peripheral T-cell Lymphoma of the Brexast: Radiologic and Pathologic Findings. J Breast Cancer 2010;13:318-322.
3Domchek SM, Hecht JL, Fleming MD, Pinkus GS, Canellos GP. Lymphomas of the breast: primary and secondary involvement. Cancer 2002;94:6-13.
4Jeanneret-Sozzi W, Taghian A, Epelbaum R, Poortmans P, Zwahlen D, Amsler B, Villette S, Belkacémi Y, Nguyen T, Scalliet P, Maingon P, Gutiérrez C, Gastelblum P, Krengli M, Raad RA, Ozsahin M, Mirimanoff RO. Primary breast lymphoma: patient profile, outcome and prognostic factors. A multicentre Rare Cancer Network study. BMC Cancer 2008;8:86.
5Kong EJ, Cho IH. F-18 FDG PET/MRI findings of primary breast lymphoma in two cases: FDG PET/MRI findings of primary breast lymphoma. Clin Imaging 2015;39:682-684.
6Chaushev B, Micheva I, Mechmed M, Balev B, Bocheva Y, Ivanova D, Krasnaliev I, Lozanova R, Klisarova A, Bochev P, Dancheva J. 18F-FDG PET/CT in the diagnosis of an extranodal relapse of diffuse large B-cell lymphoma (DLBCL): a clinical case with a literature review. Nucl Med Rev Cent East Eur 2016;19:11-13.