Myocardial Ischemia on MPI SPECT in a Patient with Acute Myeloid Leukemia Without Significant Coronary Artery Disease
PDF
Cite
Share
Request
Interesting Image
P: 63-65
February 2022

Myocardial Ischemia on MPI SPECT in a Patient with Acute Myeloid Leukemia Without Significant Coronary Artery Disease

Mol Imaging Radionucl Ther 2022;31(1):63-65
1. University Hospital of Ioannina, Department of Nuclear Medicine, Ioannina, Greece
2. University Hospital of Ioannina, Department of Cardiology, Ioannina, Greece
3. University Hospital of Ioannina, Department of Neurology, Ioannina, Greece
4. University Hospital of Ioannina, Department of Hematology, Ioannina, Greece
No information available.
No information available
Received Date: 26.06.2020
Accepted Date: 18.10.2020
Publish Date: 02.02.2022
PDF
Cite
Share
Request

ABSTRACT

Herein, we report the case of a 56-year-old male patient with acute myeloid leukemia (AML) in remission who had asymptomatic myocardial ischemia on myocardial perfusion imaging and transthoracic echocardiography. Angiography did not reveal any significant coronary artery disease. Although the etiology is not entirely clear, this case suggested that myocardial perfusion imaging should be considered in patients with AML who received idarubicin to screen for possible myocardial dysfunction.

References

1
Sioka C, Exarchopoulos T, Tasiou I, Tzima E, Fotou N, Capizzello A, Ragos V, Tsekeris P, Fotopoulos A. Myocardial perfusion imaging with (99 m)Tc-tetrofosmin SPECT in breast cancer patients that received postoperative radiotherapy: a case-control study. Radiat Oncol 2011;6:151.
2
Giannopoulos S, Markoula S, Sioka C, Zouroudi S, Spiliotopoulou M, Naka KK, Michalis LK, Fotopoulos A, Kyritsis AP. Detecting myocardial ischemia with 99mtechnetium-tetrofosmin myocardial perfusion imaging in ischemic stroke. Neurohospitalist 2017;7:164-168.
3
Roberts WC, Bodey GP, Wertlake PT. The heart in acute leukemia. A study of 420 autopsy cases. Am J Cardiol 1968;21:388-412.
4
Sioka C, Papadimitropoulos K, Michalis L, Pappas K, Lakkas L, Fotopoulos A, Dounousi E. Myocardial ischemia with normal coronary angiography in a chronic kidney disease patient. Cardiol J 2019;26:620-621.
5
Kotsalou I, Georgoulias P, Karydas I, Fourlis S, Sioka C, Zoumboulidis A, Demakopoulos N. A rare case of myocardial infarction and ischemia in a cannabis-addicted patient. Clin Nucl Med 2007;32:130-131.
6
Cohen Y, Amir G, Da’as N, Gillis S, Rund D, Polliack A. Acute myocardial infarction as the presenting symptom of acute myeloblastic leukemia with extreme hyperleukocytosis. Am J Hematol 2002;71:47-49.
7
Khan AA, Ashraf A, Singh R, Rahim A, Rostom W, Hussain M, Renner I, Collins NJ. Incidence, time of occurrence and response to heart failure therapy in patients with anthracycline cardiotoxicity. Intern Med J 2017;47:104-109.
8
Prenner SB, Franken AA, Murphy IG, Mikati IA. Rapid reversal of focal left ventricular hypertrophy and systolic dysfunction resulting from myocardial infiltration by acute lymphoblastic leukemia. Circulation 2016;133:678-679.