Abstract
A 68-year-old man with progressive exertional dyspnea after an upper respiratory tract infection underwent contrast-enhanced thorax computed tomography (CT) to exclude pulmonary thromboembolism. The radiological findings suggested pneumonia or alveolar edema. 18F-Fluorodeoxyglucose positron emission tomography/CT (18F-FDG PET) scan was conducted due to progressive radiological findings. It revealed increased FDG uptake in the prostate gland, mediastinal, abdominopelvic multiple lymph nodes and bilateral lung lesions. 68Ga- prostate-specific membrane antigen-11 (PSMA) PET/CT scan was performed due to low FDG uptake in the lymph nodes and elevated plasma total prostate-specific antigen values. Moderate to high PSMA uptake corresponded to the localizations of FDG uptake on PET/CT. Furthermore, histopathological and immunohistochemical examinations demonstrated that the bilateral lung lesions and bilateral pleural effusion were compatible with metastases from prostate adenocarcinoma.
Keywords:
Prostate cancer, 68Ga-PSMA PET/CT, pulmonary lymphangitic spread, pleural metastasis, pneumonia, 18F-FDG PET/CT
Ethics
Informed Consent: Written informed consent was obtained from the patient.
Authorship Contributions
Surgical and Medical Practices: N.A.D., Concept: E.T., A.N.Ç., Ö.Ö., Data Collection or Processing: E.T., A.Ç., Analysis or Interpretation: N.A.D., Ö.Ö., Literature Search: A.Ç., B.B., Writing: N.A.D.
Conflict of Interest: No conflicts of interest were declared by the authors.
Financial Disclosure: The authors declare that this study has received no financial support.
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