ABSTRACT
A 54-year-old man, with previous history of neurogenic heterotopic ossification (HO) in muscles around the left hip following a spinal cord injury ten months earlier, was referred to our nuclear medicine center for an 18fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) to rule out a spondylodiscitis. No sign of spondylodiscitis was found on 18F-FDG PET/CT, but images revealed an increased 18F-FDG uptake in HO areas, matching with ongoing osteoblastic activity on a following bone scan.
Keywords:
Heterotopic ossification, bone scan, 18F-FDG PET/CT
References
1
Wittenberg RH, Peschke U, Bötel U. Heterotopic ossification after spinal cord injury. Epidemiology and risk factors. J Bone Joint Surg Br 1992;74:215-218.
2
Meyers C, Lisiecki J, Miller S, Levin A, Fayad L, Ding C, Sono T, McCarthy E, Levi B, James AW. Heterotopic ossification: a comprehensive review. JBMR Plus 2019;3:e10172.
3
Cipriano CA, Pill SG, Keenan MA. Heterotopic ossification following traumatic brain injury and spinal cord injury. J Am Acad Orthop Surg 2009;17:689-697.
4
Freed JH, Hahn H, Menter R, Dillon T. The use of three-phase bone scan in the early diagnosis of heterotopic ossification (HO) and in the evaluation of Didronel therapy. Paraplegia 1982;20:208-216.
5
Lin Y, Lin WY, Kao CH, Tsai SC. Easy interpretation of heterotopic ossification demonstrated on bone SPECT/CT. Clin Nucl Med 2014;39:62-63.
6
Koob M, Durckel J, Dosch JC, Entz-Werle N, Dietemann JL. Intercostal myositis ossificans misdiagnosed as osteosarcoma in a 10-year-old child. Pediatr Radiol 2010;40:S34-37.
7
Clarençon F, Larousserie F, Babinet A, Zylbersztein C, Talbot JN, Kerrou K. FDG PET/CT findings in a case of myositis ossificans circumscripta of the forearm. Clin Nucl Med 2011;36:40-42.
8
Costelloe CM, Murphy WA Jr, Chasen BA. Musculoskeletal pitfalls in 18F-FDG PET/CT: pictorial review. AJR Am J Roentgenol 2009;193:WS1-WS13.