E-ISSN: 2147-1959
Magnetic Resonance Imaging Signal Changes Mimicking Bone Metastasis in Patients Receiving Bisphosphonate Therapy
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VOLUME: 30 ISSUE: 2
P: 122-125
June 2021

Magnetic Resonance Imaging Signal Changes Mimicking Bone Metastasis in Patients Receiving Bisphosphonate Therapy

Mol Imaging Radionucl Ther 2021;30(2):122-125
DOI: 10.4274/mirt.galenos.2020.49091
İpek Tamsel 1
Mehmet Argın 1
Ayşegül Akgün 2
1. Ege University Faculty of Medicine Hospital, Department of Radiology, İzmir, Turkey
2. Ege University Faculty of Medicine Hospital, Department of Nuclear Medicine, İzmir, Turkey
No information available.
No information available
Received Date: 15.03.2020
Accepted Date: 31.05.2020
Publish Date: 03.06.2021
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ABSTRACT

Bisphosphonates are inorganic pyrophosphate agents that reduce bone turnover. These agents reduce bone pain and delay skeletal complications, such as fractures in patients with metastatic lytic lesions, malignant-related hypercalcemia, multiple myeloma, Paget’s disease of bone, and osteoporosis. Osteonecrosis, developing in the jaw bones specifically, has been described as a complication associated with the use of bisphosphonates. In this report, we presented osteonecrosis-like magnetic resonance imaging findings that can be confused with bone metastasis in two patients who underwent long-term bisphosphonate treatment and the value of bone scan and 18flor-fluorodeoxyglucose positron emission tomography/computerized tomography in the differential diagnosis.

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