Long-term Intense <sup>18</sup>F-FDG Uptake by the Homeostatic Matrix-associated Inflammatory Response May Mimic Malignancy Recurrence
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P: 233-236
October 2023

Long-term Intense 18F-FDG Uptake by the Homeostatic Matrix-associated Inflammatory Response May Mimic Malignancy Recurrence

Mol Imaging Radionucl Ther 2023;32(3):233-236
1. Niğde Ömer Halisdemir University Training and Research Hospital, Department of Nuclear Medicine, Niğde, Türkiye
2. Ege University Faculty of Medicine, Department of Nuclear Medicine, İzmir, Türkiye
No information available.
No information available
Received Date: 12.01.2023
Accepted Date: 04.02.2023
Publish Date: 20.10.2023
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ABSTRACT

A 70-year-old man underwent right upper lobectomy for lung adenocarcinoma. During the operation, hemostatic matrix (as known Floseal®) was used to prevent pulmonary laceration-associated bleeding. When 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography was performed for staging after surgery, intense 18F-FDG uptake was observed in the cicatricial fibrotic tissue in the operation area, and no significant change was observed in that area during the 4-year follow-up. Because it remained stable for several years without treatment, this finding was thought to be due to a foreign body reaction caused by the homeostatic material.

Keywords:
Homeostatic matrix
false positivity
positron emission tomography
lung cancer

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