<sup>18</sup>F-Sodium Fluoride (NaF) Uptake in Calcified Bladder Carcinoma: Double Density Sign
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P: 190-192
October 2021

18F-Sodium Fluoride (NaF) Uptake in Calcified Bladder Carcinoma: Double Density Sign

Mol Imaging Radionucl Ther 2021;30(3):190-192
1. Kuwait Cancer Control Center, Department of Nuclear Medicine, Shuwaikh, Kuwait
2. Jack Brignall PET/CT Centre, Castle Hill Hospital, Cottingham, United Kingdom
No information available.
No information available
Received Date: 05.05.2020
Accepted Date: 16.07.2020
Publish Date: 15.10.2021
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ABSTRACT

18F-Sodium fluoride (NaF) is primarily a skeletal imaging agent which can be localized in extraosseous calcified foci. Here, we describe a case of a 48-year-old man with bladder carcinoma referred for staging using 18F-NaF positron emission tomography/computed tomography (PET/CT). 18F-NaF PET/CT detected a calcified soft tissue mass in the urinary bladder. Extraosseous 18F-NaF uptake is often encountered and these non-osseous findings could possibly provide important diagnostic information. Thus, recognition of extraosseous 18F-NaF activity has implications for accurate staging and management.

References

1Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J Clin 2016;66:7-30.
2Babaian RJ, Johnson DE, Llamas L, Ayala AG. Metastases from transitional cell carcinoma of urinary bladder. Urology 1980;16:142-144.
3Kirkali Z, Chan T, Manoharan M, Algaba F, Busch C, Cheng L, Kiemeney L, Kriegmair M, Montironi R, Murphy WM, Sesterhenn IA, Tachibana M, Weider J. Bladder cancer: epidemiology, staging and grading, and diagnosis. Urology 2005;66(6 Suppl 1):4-34.
4Czernin J, Satyamurthy N, Schiepers C. Molecular mechanisms of bone 18F-NaF deposition. J Nucl Med 2010;51:1826-1829.
5Araz M, Aras G, Küçük ÖN. The role of 18F-NaF PET/CT in metastatic bone disease. J Bone Oncol 2015;4:92-97.
6Usmani S, Gnanasegaran G, Marafi F, Esmail A, Ahmed N, Van den Wyngaert T. The clinical significance of incidental soft tissue uptake on whole body 18F-sodium fluoride bone PET-CT. Clin Radiol 2019;74:95-110.
7Korkmaz U, Ustun F. 18F-NaF PET/CT and Extraordinary Involvement: Non-calcific Brain Involvement in a Prostate Cancer Case. Mol Imaging Radionucl Ther 2020;29:41-44.
8Sheth S, Colletti PM. Atlas of sodium fluoride PET bone scans: atlas of NaF PET bone scans. Clin Nucl Med 2012;37:e110-116.
9Van Der Gucht A, Galat A, Rosso J, Guellich A, Garot J, Bodez D, et al. [18F]-NaF PET/CT imaging in cardiac amyloidosis. J Nucl Cardiol 2016;23:846-849.
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