E-ISSN: 2147-1959
<sup>18</sup>F-FDG PET/CT Showing Rare Mediastinal Growing Teratoma Syndrome Following Chemotherapy
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VOLUME: 31 ISSUE: 3
P: 239-241
October 2022

18F-FDG PET/CT Showing Rare Mediastinal Growing Teratoma Syndrome Following Chemotherapy

Mol Imaging Radionucl Ther 2022;31(3):239-241
DOI: 10.4274/mirt.galenos.2021.54775
Mihoko Sasahara 1
Takashi Abe 2
Yoichi Otomi 1
Yumi Abe 2
Hiroaki Toba 3
Takayoshi Shinya 1
Hideki Otsuka 1
Masafumi Harada 1
1. Tokushima University, Department of Radiology, Tokushima, Japan
2. Nagoya University Hospital, Department of Radiology, Nagoya, Japan
3. Tokushima University, Department of Thoracic and Endocrine Surgery and Oncology, Tokushima, Japan
No information available.
No information available
Received Date: 27.05.2021
Accepted Date: 05.09.2021
Publish Date: 19.10.2022
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ABSTRACT

Growing teratoma syndrome (GTS) is a condition in which poorly differentiated cells in a mixed-germ cell tumor (GCT) regress after chemotherapy, and the number of well-differentiated components increases. A 60-year-old man had an 8.0 cm mediastinal tumor with strong 18F-fluorodeoxyglucose (FDG) uptake [maximum standardized uptake value (SUVmax): 9.2], which was diagnosed as a GCT. After chemotherapy, serum alpha fetoprotein, beta-human chorionic gonadotropin, and tumor 18F-FDG uptake decreased (SUVmax: 3.9), but the tumor volume increased. The tumor was completely resected, and pathology confirmed the diagnosis of GTS. 18F-FDG positron emission tomography after chemotherapy reflects the proliferation of highly differentiated tumor components with poor 18F-FDG uptake.

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