<sup>18</sup>F-FDG PET/CT Correctly Differentiates Idiopathic Pericarditis From Recurrent Lymphoma in a Patient with Primary Mediastinal Lymphoma
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18F-FDG PET/CT Correctly Differentiates Idiopathic Pericarditis From Recurrent Lymphoma in a Patient with Primary Mediastinal Lymphoma

Mol Imaging Radionucl Ther 0;0(0):0-0
1. King Chulalongkorn Memorial Hospital, Nuclear Medicine Unit, Bangkok, Thailand
2. Chulalongkorn University Faculty of Medicine, Chulalongkorn University International Doctor of Medicine program (CU-MEDi), Bangkok, Thailand
3. Phramongkutklao College of Medicine, Bangkok, Thailand
4. Chulalongkorn University Faculty of Medicine, Department of Radiology, Nuclear Medicine Unit, Bangkok, Thailand
5. Chulalongkorn University Faculty of Medicine, King Chulalongkorn Memorial Hospital, Department of Radiology, Diagnostic Radiology Unit, Bangkok, Thailand
No information available.
No information available
Received Date: 27.11.2023
Accepted Date: 29.02.2024
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ABSTRACT

A man in his 30s awaiting end-of-treatment 18F-fluorodeoxyglucose positron emission tomography/CT (18F-FDG PET/CT) for primary mediastinal B-cell lymphoma developed chest pain and pericardial effusion. His interim 18F-FDG PET/CT showed complete metabolic responses. His blood test revealed elevated levels of inflammatory markers, including C-reactive protein of 204.1 mg/L and erythrocyte sedimentation rate of 106 mm/h. His pericardial biopsy revealed organizing fibrinous pericarditis with hemosiderin pigment deposition and no evidence of malignancy or granuloma. The 18F-FDG PET/CT performed during this episode of illness revealed a mild degree of 18F-FDG uptake along the pericardial lining [maximum standardized uptake value (SUVmax) =6.76] compared with the blood pool activity (SUVmax =3.17), which favors pericarditis over relapsed lymphoma. His symptoms subsided 2 weeks after treatment with an non-steroidal anti-inflammatory drug, and he had no sign of relapsed lymphoma on subsequent follow-ups.

Keywords: Nuclear medicine, pericarditis, non-Hodgkins lymphoma, cardiology

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