E-ISSN: 2147-1959
Increased 18F-FDG Uptake in the Axillary Lymph Nodes of the Vaccinated Side Associated with COVID-19 Vaccination
PDF
Cite
Share
Request
Interesting Image
VOLUME: 31 ISSUE: 2
P: 169 - 171
June 2022

Increased 18F-FDG Uptake in the Axillary Lymph Nodes of the Vaccinated Side Associated with COVID-19 Vaccination

Mol Imaging Radionucl Ther 2022;31(2):169-171
Yoichi Otomi 1
Saho Irahara 1
Hiroaki Inoue 2
Takayoshi Shinya 1
Hideki Otsuka 1
Masafumi Harada 1
1. Tokushima University, Department of Radiology, Tokushima, Japan
2. Tokushima University, Department of Thoracic and Endocrine Surgery and Oncology, Tokushima, Japan
No information available.
No information available
Received Date: 02.04.2021
Accepted Date: 12.05.2021
Publish Date: 27.06.2022
PDF
Cite
Share
Request

ABSTRACT

A 50-year-old female patient underwent (18fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) following modified radical mastectomy for cancer of the left breast. Ten days before the PET/CT, the coronavirus disease-2019 (COVID-19) vaccine was injected intramuscularly into the right deltoid muscle. Increased (18F-FDG uptake of maximum standardized uptake value (11.0) was observed in the lymph nodes of the right axilla, which had not been observed in the previous PET/CT. The size of the oval-shaped lymph nodes was up to approximately 11×9 mm; however, it was larger than that observed on the previous PET/CT. We contemplate that the increased (18F-FDG uptake was a reactive change in the lymph nodes associated with the COVID-19 vaccine.

Keywords:
COVID-19, vaccination, 18F-FDG PET/CT

References

1
Johnson BJ, Van Abel KM, Ma DJ, Johnson DR. 18F-FDG-avid axillary lymph nodes after COVID-19 vaccination. J Nucl Med 2021;62:1483-1484.
2
Avner M, Orevi M, Caplan N, Popovtzer A, Lotem M, Cohen JE. COVID-19 vaccine as a cause for unilateral lymphadenopathy detected by 18F-FDG PET/CT in a patient affected by melanoma. Eur J Nucl Med Mol Imaging 2021;48:2659-2660.
3
Ahmed N, Muzaffar S, Binns C, Ilyas MW, Usmani S. COVID-19 Vaccination Manifesting as Incidental Lymph Nodal Uptake on 18F-FDG PET/CT. Clin Nucl Med 2021;46:435-436.
4
Nawwar AA, Searle J, Hagan I, Lyburn ID. COVID-19 vaccination induced axillary nodal uptake on [18F]FDG PET/CT. Eur J Nucl Med Mol Imaging 2021;48:2655-2656.
5
Xu G, Lu Y. COVID-19 mRNA vaccination-induced lymphadenopathy mimics lymphoma progression on FDG PET/CT. Clin Nucl Med 2021;46:353-354.
6
Eifer M, Eshet Y. Imaging of COVID-19 vaccination at FDG PET/CT. Radiology 2021;299:E248.
7
Panagiotidis E, Exarhos D, Housianakou I, Bournazos A, Datseris I. FDG uptake in axillary lymph nodes after vaccination against pandemic (H1N1). Eur Radiol 2010;20:1251-1253.
8
Thomassen A, Lerberg Nielsen A, Gerke O, Johansen A, Petersen H. Duration of 18F-FDG avidity in lymph nodes after pandemic H1N1v and seasonal influenza vaccination. Eur J Nucl Med Mol Imaging 2011;38:894-898.
2024 ©️ Galenos Publishing House