E-ISSN: 2147-1959
Increased Bone Marrow <sup>18</sup>F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia
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VOLUME: 29 ISSUE: 1
P: 45-48
February 2020

Increased Bone Marrow 18F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia

Mol Imaging Radionucl Ther 2020;29(1):45-48
DOI: 10.4274/mirt.galenos.2019.03064
Luca Filippi
1. Santa Maria Goretti Hospital, Clinic of Nuclear Medicine, Latina, Italy
No information available.
No information available
Received Date: 09.08.2019
Accepted Date: 30.09.2019
Publish Date: 17.02.2020
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ABSTRACT

A 57-year-old male with history of thalassemia intermedia and hepatocellular carcinoma underwent a positron emission tomography/computed tomography (PET/CT) scan with 18F-choline before radioembolization procedure with 90Y-microspheres. The PET/CT scan with 18F-choline demonstrated highly increased tracer incorporation within a gross lesion in the hepatic dome coupled with diffuse activity in bone marrow, this latter aspect was probably due to the compensatory hematopoiesis stimulation induced by chronic hemolysis. This pattern of skeletal 18F-choline uptake should be considered as a peculiar PET/CT finding in thalassemic patients.

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