Abstract
Metastatic calcification is characterized by abnormal deposition of calcium in extraosseous tissues resulting from disruption of calcium-phosphorus homeostasis. It occurs without tissue damage and is usually seen in normal organs. It is most commonly observed in patients with chronic renal failure, paraneoplastic hypercalcemia, and vitamin D intoxication. Metabolic superscan is characterized by diffusely increased skeletal activity with suppressed renal visualization, often without soft-tissue involvement. This pattern reflects altered radiotracer biodistribution secondary to severe metabolic bone turnover. We report a case of multiple myeloma in which diffuse 99mTc-MDP uptake was observed in the stomach on a metabolic superscan.
Keywords:
Multiple myeloma, metabolic superscan, gastric uptake, hypercalcemia, methylene diphosphonate, bone scan
Ethics
Informed Consent: Written informed consent for the anonymized publication of clinical data and images was obtained from the patient prior to the initiation of the study.
Authorship Contributions
Surgical and Medical Practices: G.B.B., Ö.Ş., G.B., H.A., F.T., Concept: G.B.B., G.B., E.B., Design: G.B.B., H.A., E.B., Data Collection or Processing: G.B.B., H.A., E.B., Analysis or Interpretation: Ö.Ş., H.A., Literature Search: G.B.B., F.T., Writing: G.B.B., Ö.Ş., F.T., E.B.
Conflict of Interest: No conflicts of interest were declared by the authors.
Financial Disclosure: The authors declare that this study has received no financial support.
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