Diagnosis of Atypical Medullary Metastasis in Melanoma Using 18F-FDG PET/CT
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VOLUME: 34 ISSUE: 1
P: 61 - 63
February 2025

Diagnosis of Atypical Medullary Metastasis in Melanoma Using 18F-FDG PET/CT

Mol Imaging Radionucl Ther 2025;34(1):61-63
1. Mohammed V Military Training Hospital Clinic of Nuclear Medicine, Rabat, Morocco
No information available.
No information available
Received Date: 01.05.2024
Accepted Date: 05.06.2024
Online Date: 07.02.2025
Publish Date: 07.02.2025
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Abstract

As part of the therapeutic evaluation, positron emission tomography/computed tomography (PET/CT) using 18F-fluorodeoxyglucose (18F-FDG) was performed on a 39-year-old patient with metastatic melanoma of the left thigh who was subsequently receiving immunotherapy. The examination revealed pathologic hypermetabolic foci in the lymph nodes and liver along with a highly suspicious pathologic hypermetabolic foci in the spinal marrow at the level of the first lumbar vertebra (L1). The presence of such a hypermetabolic focus can significantly decrease survival duration, highlighting the importance of early detection. PET/CT with 18F-FDG proved to be more sensitive and specific than CT alone in identifying occult distant metastases, as the latter may underestimate malignant involvement of the spinal marrow.

Keywords:
PET-18F-FDG, melanoma, spinal marrow, metastasis

Ethics

Informed Consent: Informed consents of the patient was obtained.

Authorship Contributions

Concept: C.B., S.O.N., K.B., O.A.S., Y.B., A.D., Design: C.B., S.O.N., O.A.S., Y.B., A.D., Data Collection or Processing: C.B., Analysis or Interpretation: C.B., S.O.N., A.D., Literature Search: C.B., Writing: C.B.
Conflict of Interest: No conflicts of interest were declared by the authors.
Financial Disclosure: The authors declare that this study has received no financial support.

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