Abstract
A 58-year-old man presenting with dyspnea, weight loss, and night sweating underwent 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) because of a suspicion of malignancy. 18F-FDG PET/CT demonstrated mild to moderate uptake on nasal, cricoid, and tracheobronchial tree cartilages and costovertebral junctions. The diagnosis was relapsing polychondritis, which is a rare multisystem disease characterized by inflammation of cartilage. In addition, subsequent 18F-FDG PET/CT after treatment showed complete metabolic response.
References
1Luthra HS. Relapsing polychondritis. Primer on the rheumatic diseases, Springer 2008;451-454.
2Longo L, Greco A, Rea A, Lo Vasco VR, De Virgilio A, De Vincentiis M. Relapsing polychondritis: A clinical update. Autoimmun Rev 2016;15:539-543.
3Kingdon J, Roscamp J, Sangle S, D’Cruz D. Relapsing polychondritis: a clinical review for rheumatologists. Rheumatology (Oxford) 2018;57:1525-1532.
4Borgia F, Giuffrida R, Guarneri F, Cannavò SP. Relapsing polychondritis: an updated review. Biomedicines 2018;6:84.
5Zhuang H, Codreanu I. Growing applications of FDG PET-CT imaging in non-oncologic conditions. J Biomed Res 2015;29:189-202.
6Pijl JP, Nienhuis PH, Kwee TC, Glaudemans AWJM, Slart RHJA, Gormsen LC. Limitations and pitfalls of FDG-PET/CT in infection and inflammation. Semin Nucl Med 2021;51:633-645.
7Kubota K, Yamashita H, Mimori A. Clinical value of FDG-PET/CT for the evaluation of rheumatic Diseases: rheumatoid arthritis, polymyalgia rheumatica, and relapsing polychondritis. Semin Nucl Med 2017;47:408-424.
8Kwok SH, Choi F. Relapsing polychondritis: the oto-rhino-tracheobronchial triad on 18 F-FDG PET/CT. Clin Nucl Med 2023;48:699-701.
