Complete Treatment Response of Isolated Lacrimal IgG4-Related Disease on 18F-FDG PET/CT Imaging
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26 November 2025

Complete Treatment Response of Isolated Lacrimal IgG4-Related Disease on 18F-FDG PET/CT Imaging

Mol Imaging Radionucl Ther. Published online 26 November 2025.
1. İstanbul University-Cerrahpaşa Cerrahpaşa Faculty of Medicine, Department of Nuclear Medicine, İstanbul, Türkiye
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Received Date: 18.02.2025
Accepted Date: 26.10.2025
E-Pub Date: 26.11.2025
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Abstract

We describe a case of a 57-year-old woman with isolated immunoglobulin G4-related disorder affecting her lacrimal glands. Pre-treatment 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG PET/CT) showed diffuse enlargement and increased FDG uptake in both lacrimal glands. After immunosuppressive treatment, 18F-FDG PET/CT showed no significant FDG uptake, and the sizes of both glands returned to normal.

Keywords:
Lacrimal, IgG4, FDG, PET, treatment

Ethics

Informed Consent: Informed consent was obtained from the patient for the use of their imaging data.

Authorship Contributions

Surgical and Medical Practices: A.K., S.A., Concept: A.K., S.A., O.E.Ş., L.U.B., S.S., K.S., H.B.S., Design: A.K., S.A., Data Collection or Processing: A.K., S.A., Analysis or Interpretation: A.K., S.A., O.E.Ş., L.U.B., S.S., K.S., H.B.S., Literature Search: A.K., Writing: A.K.
Conflict of Interest: No conflicts of interest were declared by the authors.
Financial Disclosure: The authors declare that this study has received no financial support.

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