E-ISSN: 2147-1959
Comparative Findings Between <sup>68</sup>Ga-PSMA and <sup>18</sup>F-FDG PET/CT for Hepatocellular Carcinoma
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VOLUME: 29 ISSUE: 3
P: 135-138
October 2020

Comparative Findings Between 68Ga-PSMA and 18F-FDG PET/CT for Hepatocellular Carcinoma

Mol Imaging Radionucl Ther 2020;29(3):135-138
DOI: 10.4274/mirt.galenos.2020.50455
Seval Erhamamcı 1
Nesrin Aslan 2
1. Başkent University Faculty of Medicine, Ankara; Başkent University İstanbul Hospital, Department of Nuclear Medicine, İstanbul, Turkey
2. Neolife Medical Center, Clinic of Nuclear Medicine, İstanbul, Turkey
No information available.
No information available
Received Date: 26.04.2020
Accepted Date: 29.06.2020
Publish Date: 19.10.2020
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ABSTRACT

We have reported here the case of a 69-year-old man who presented with spinal cord compression due to bone metastases as the first manifestation of hepatocellular carcinoma (HCC). For the initial staging, the patient underwent 18F-fluorodeoxyglucose (FDG) positron emission tomography/computerized tomography (PET/CT) imaging, which demonstrated mild 18F-FDG uptake in the multiple expansile osteolytic bone lesions, but no remarkable atypical 18F-FDG uptake in the liver lesion on low-doses CT. An additional PET/CT scan was performed to evaluate the prostate-specific membrane antigen (PSMA) expression, which has recently been reported to be a potential biological marker in a variety of tumors including HCC. High PSMA uptake was recorded in both the metastatic bone lesions and the primary liver lesion/tumor by the 68Ga-PSMA PET/CT.

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