Abstract
Lung cancer is the leading cause of cancer-related deaths worldwide. While metastasis to distant organs is commonly described, renal metastasis remains rare and uncommon. In this paper, we present the case of a 53-year-old man with a history of left apical lung adenocarcinoma who underwent fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (CT) for suspected recurrence. The scan revealed a recurrent pulmonary mass with metastatic spread, notably showing intense bilateral focal FDG uptake in the kidneys. A metastatic origin was suspected and subsequently confirmed by CT-guided renal biopsy.
Although rare and typically observed in advanced stages of the disease, this case underscores the importance of carefully evaluating focal FDG uptake in the renal cortex to ensure accurate staging and optimal management of oncologic patients.
Keywords:
Fluorodesoxyglucose, positron emission tomography/CT, lung adenocarcinoma, renal metastasis
Ethics
Informed Consent: Informed consent was obtained from the patient for publication
Authorship Contributions
Surgical and Medical Practices: I.E.M., A.M., I.G., H.G., Concept: I.E.M., A.M., K.B., H.G., Design: I.E.M., K.B., Data Collection or Processing: I.E.M., A.M., Analysis or Interpretation: I.E.M., A.M., I.G., H.G., Literature Search: I.E.M., Writing: I.E.M., A.M.
Conflict of Interest: No conflicts of interest were declared by the authors.
Financial Disclosure: The authors declare that this study has received no financial support.
References
1Lian H, Pan X, Hong B, Min J, Huang F. Metastases to the kidney from primary lung cancer: clinicopathological analysis of six cases in a single center. Diagn Pathol. 2023;18:60.
2Zhou C, Urbauer DL, Fellman BM, Tamboli P, Zhang M, Matin SF, Wood CG, Karam JA. Metastases to the kidney: a comprehensive analysis of 151 patients from a tertiary referral centre. BJU Int. 2016;117:775-782.
3Halaç M, Özhan M, Yilmaz Aksoy S, Vatankulu B, Aliyev A, Asa S, Atahan E, Sağer MS, Sönmezoğlu K. The role of FDG-PET/CT in detecting unsuspected and unknown distant metastasis in the initial staging of NSCLC. Turk J Med Sci. 2014;44:1029-1040.
4Aras M, Dede F, Ones T, Inanır S, Erdil TY, Turoğlu HT. Is The value of FDG PET/CT in evaluating renal metastasis underestimated? A case report and review of the literature. Mol Imaging Radionucl Ther. 2013;22:109-112.
5Zhang J, Dong A, Wang Y. FDG PET/CT in solitary isolated renal metastasis from squamous cell lung cancer. Clin Nucl Med. 2024;49:e50-e51.
