A Rare Case of Triple Primary Malignant Neoplasms (RCC and Colon Cancer) Detected by 18F-FDG PET/CT
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VOLUME: 34 ISSUE: 1
P: 55 - 57
February 2025

A Rare Case of Triple Primary Malignant Neoplasms (RCC and Colon Cancer) Detected by 18F-FDG PET/CT

Mol Imaging Radionucl Ther 2025;34(1):55-57
1. Alexandrovska University Hospital Department of Nuclear Medicine, Sofia, Bulgaria
No information available.
No information available
Received Date: 13.02.2024
Accepted Date: 14.05.2024
Online Date: 07.02.2025
Publish Date: 07.02.2025
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Abstract

Multiple primary malignancies are not uncommon in daily oncology practice, even though their frequency in the same or different organ systems varies. Regardless, early detection and proper planning of therapeutic approaches are essential for successful management. Here, we present a 73-years-old male with adenocarcinoma of the sigmoid who was referred for initial staging with 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT). 18F-FDG PET/CT revealed two metabolically active formations in the sigmoid and ascending colon and a large, heterogeneous tumor lesion in the middle and lower third of the left kidney, with increased 18F-FDG uptake in soft tissue components, suggesting the presence of synchronous neoplasms. The scan also showed 18F-FDG-positive multiple metabolically active lytic bone lesions with soft tissue components, small pulmonary nodules, and mediastinal/hilar lymph nodes with mildly elevated metabolic activity, suggesting secondary foci. Considering these findings, the patient was referred for histological evaluation.

Keywords:
18F-FDG PET/CT, synchronous tumors, colon cancer, renal cell carcinoma

Ethics

Informed Consent: Institutional review board approval was not required. Informed consent was obtained from each participant.

Authorship Contributions

Concept: P.N., V.H., Design: P.N., V.H., G.G., M.I., Data Collection or Processing: Y.G., S.V., G.G., E.R., Analysis or Interpretation: G.G., E.R., M.I., Literature Search: Y.G., S.V., G.G., Writing: P.N., V.H., M.I.
Conflict of Interest: No conflicts of interest were declared by the authors.
Financial Disclosure: The authors declare that this study has received no financial support.

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