ABSTRACT
Pulmonary alveolar microlithiasis is a rare disease characterized by accumulating intraalveolar small calcium phosphate stones. The disease is slow and does not show any signs in the early stages, but the shortness of breath, cough, and right heart failure may develop as it progresses. Methylene diphosphonate used in bone scintigraphy shows high uptake of calcium deposits in the alveoli and causes diffuse increased radiopharmaceutical uptake in the lungs.
References
1Kashyap S, Mohapatra PR. Pulmonary alveolar microlithiasis. Lung India 2013;30:143-147.
2Alkhankan E, Yamin H, Bukamur H, Alkhankan F, Shweihat Y, Zeid F. Pulmonary alveolar microlithiasis diagnosed with radiography, CT, and bone scintigraphy. Radiol Case Rep 2019;14:775-777.
3Arpağ H, Sayan M, Atilla N, Bozkuş F, Bahar AY, Kahraman H, Tokur M. A case of pulmonary alveolar microlithiasis diagnosed by transbronchial biopsy. Turk Thorac J 2017;18:134-136.
4Simon CT, Lewis TC, Neemuchwala F, Arteta M, Rabah R. Pulmonary alveolar microlithiasis: a case report with a novel mutation in the SLC34A2 gene and review of the literature. Human Pathology: Case Reports 2018;13:33-35.
5Ferreira Francisco FA, Pereira e Silva JL, Hochhegger B, Zanetti G, Marchiori E. Pulmonary alveolar microlithiasis. State-of-the-art review. Respir Med 2013;107:1-9.
6Castellana G, Castellana G, Gentile M, Castellana R, Resta O. Pulmonary alveolar microlithiasis: review of the 1022 cases reported worldwide. Eur Respir Rev 2015;24:607-620.
7Basu S, Shah M, Joshi JM, Lad S. Imaging calcific concretions of pulmonary alveolar microlithiasis with PET: insight into disease pathophysiology. Clin Nucl Med 2012;37:707-708.
8Tanrıkulu AÇ, Dağlı AC, Şenyiğit A, Nazaroğlu H, Babayiğit C. Pulmonary alveolar microlithiasis: radiologic findings of eight cases in Turkey. Turkiye Klinikleri J Med Sci 2010;30:713-720.
