E-ISSN: 2147-1959
A Case with <sup>68</sup>Ga-FAPI Positive and <sup>18</sup>F-FDG Negative Breast Cancer
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VOLUME: 30 ISSUE: 3
P: 201-204
October 2021

A Case with 68Ga-FAPI Positive and 18F-FDG Negative Breast Cancer

Mol Imaging Radionucl Ther 2021;30(3):201-204
DOI: 10.4274/mirt.galenos.2021.69926
Halil Kömek 1
Cihan Gündoğan 1
Hülya Etem 2
Canan Can 1
1. University of Health Sciences Turkey, Gazi Yaşargil Training and Research Hospital, Clinic of Nuclear Medicine, Diyarbakır, Turkey
2. University of Health Sciences Turkey, Gazi Yaşargil Training and Research Hospital, Clinic of Pathology, Diyarbakır, Turkey
No information available.
No information available
Received Date: 18.05.2021
Accepted Date: 08.07.2021
Publish Date: 15.10.2021
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ABSTRACT

A female patient diagnosed of infiltrative breast carcinoma using tru-cut biopsy underwent 18flourine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for staging. The tumor was located in the superior external quadrant of the right breast, and did not exhibit pathological uptake in 18F-FDG PET/CT. Later, gallium-68 (68Ga) fibroblast activation protein-specific inhibitor (FAPI)-04 PET/CT imaging was performed and the primary tumor showed intense radiotracer accumulation. This presumes that 68Ga-FAPI PET/CT imaging is superior to 18F-FDG imaging in detecting the primary tumor in breast cancer, thereby suggesting the replacement of FAPI by 18F-FDG in breast-cancer staging in the future.

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