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Testicular Metastasis of Jejunal Neuroendocrine Tumor on ⁶⁸Ga-DOTATATE PET/CT

10.4274/mirt.galenos.2022.06926

• Ömer Faruk Şahin
• Özge Erol Fenercioğlu
• Ediz Beyhan
• Tevfik Fikret Çermik
• Nurhan Ergül

Received Date: 20.06.2022 Accepted Date: 09.10.2022 Mol Imaging Radionucl Ther 2023;32(2):156-158 PMID: 37337848

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Neuroendocrine tumors are slow-growing tumors originating from neuroendocrine cells and capable of metastasis. Most of them are found in the gastrointestinal tract; however, they can also be rarely seen in other organs. Testicular neuroendocrine tumors account for less than 1% of all testicular neoplasms. They may present as primary testicular or secondary tumors from extratesticular sources. Jejunal neuroendocrine tumor metastasis to the testis is extremely rare. We present the case of a 61-year-old man with a jejunal neuroendocrine tumor and metastases to bilateral testicles revealed on Gallium-68-DOTATATE positron emission tomography/computed tomography.

Keywords: 68Ga-DOTATATE, testicular metastasis, jejunal neuroendocrine tumor, PET/CT

Ethics

Informed Consent: The patient consent was obtained.

Peer-review: Externally and internally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: Ö.F.Ş., Ö.E.F., E.B., T.F.Ç., N.E., Concept: T.F.Ç., N.E., Design: Ö.F.Ş., Ö.E.F., E.B., N.E., Data Collection or Processing: Ö.F.Ş., Ö.E.F., E.B., Analysis or Interpretation: Ö.F.Ş., Ö.E.F., E.B., N.E., Literature Search: Ö.F.Ş., Writing: Ö.F.Ş.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study has received no financial support.

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1. Antoniadou F, Korkolis D, Koufopoulos N, Manatakis D, Sakellariou S. A well differentiated neuroendocrine tumor of the jejunum with peritoneal carcinomatosis: a case report. Mol Clin Oncol 2018;9:651-655.
2. Landerholm K, Falkmer S, Järhult J. Epidemiology of small bowel carcinoids in a defined population. World J Surg 2010;34:1500-1505.
3. Bodei L, Ambrosini V, Herrmann K, Modlin I. Current Concepts in ⁶⁸Ga-DOTATATE imaging of neuroendocrine neoplasms: interpretation, biodistribution, dosimetry, and molecular strategies. J Nucl Med 2017;58:1718-1726.
4. Amine MM, Mohamed B, Mourad H, Majed H, Slim C, Mehdi B, Hela M, Nouri R, Rim K, Tahya B, Nabil MM. Neuroendocrine testicular tumors: a systematic review and meta-analysis. Curr Urol 2017;10:15-25. 
5. Wang WP, Guo C, Berney DM, Ulbright TM, Hansel DE, Shen R, Ali T, Epstein JI. Primary carcinoid tumors of the testis: a clinicopathologic study of 29 cases. Am J Surg Pathol 2010;34:519-524. 
6. Manna S, Narayana SM, Premalata CS. Primary neuroendocrine tumor of the testis masquerading as germ cell tumor – a case report. Eur J Med Health Science 2020;2:518.
7. Fucs M, Romero FR, Germanos de Castro M, de Carvalho Fernandes R, Camara-Lopes LH, Cardenuto Perez MD. Testicular metastasis 10 years after resection of appendiceal carcinoid. Urology 2005;65:591. 
8. Danikas D, Sachs R, Dressner RM, Arvanitis ML. Testicular metastasis from ileal carcinoid: report of a case. Dis Colon Rectum 2001;44:1365-1366. 
9. Lau HY, Lai V. Metastatic testicular carcinoid tumour. Hong Kong J Radiol 2013;16:69-73.
10. Berdjis CC, Mostofi FK. Carcinoid tumors of the testis. J Urol 1977;118:777-782. 
11. Stroosma OB, Delaere KP. Carcinoid tumours of the testis. BJU Int 2008;101:1101-1105. 
12. Cope Z. Metastasis of an argentaffin carcinoma in the testicle. British Journal Urol 1930;2:268-272.
13. Blumberg JM, Sedberry S, Kazmi SO. Bilateral asynchronous metastatic carcinoid tumor of the testis. Urology 2005;65:174.