Interesting Image

Superscan Appearance of 68Ga PSMA PET/CT in a Patient with Refractory Prostate Cancer


  • Zehra Pınar Koç
  • Pınar Pelin Özcan
  • Vehbi Erçolak
  • Mehmet Reyhan

Received Date: 17.02.2020 Accepted Date: 17.09.2020 Mol Imaging Radionucl Ther 2022;31(1):60-62 PMID: 35114754

A 64-year-old male patient with metastatic prostate carcinoma diagnosis received lutetium-177 prostate-specific membrane antigen (PSMA) treatment; however, his disease progressed. Herein, presented the final images of the patient that demonstrated a superscan appearance in the Gallium-68 PSMA positron emission tomography/computed tomography, which is a rare phenomenon.

Keywords: PSMA, 68Ga, Lu-177, prostate cancer


Informed Consent: The informed consent of the patient was obtained.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: Z.P.K., P.P.Ö., V.E., M.R., Concept: Z.P.K., P.P.Ö., Design: Z.P.K., P.P.Ö., Data Collection or Processing: Z.P.K., P.P.Ö., V.E., M.R., Analysis or Interpretation: Z.P.K., P.P.Ö., V.E., M.R., Literature Search: Z.P.K., P.P.Ö., Writing: Z.P.K., P.P.Ö.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.


  1. Kim SE, Kim DY, Lee DS, Chung JK, Lee MC, Koh CS. Absent or faint renal uptake on bone scan. Etiology and significance in metastatic bone disease. Clin Nucl Med 1991;16:545-549.
  2. Kim DW, Kim CG, Park SA, Jung SA, Yang SH. Metabolic super scan in F-FDG PET/CT imaging. J Korean Med Sci 2010;25:1256-1257.
  3. Bailly M, Besse H, Kerdraon R, Metrard G, Gauvain S. 18F-FDG PET/CT superscan in prostate cancer. Clin Nucl Med 2014;39:912-914.
  4. Parida GK, Soundararajan R, Passah A, Bal C, Kumar R. Metabolic Skeletal superscan on 18F-FDG PET/CT in a case of acute lymphoblastic leukemia. Clin Nucl Med 2015;40:567-568.
  5. Grellier JF, Lussato D, Queneau M, Guernou M, Songy B. Secondary hyperparathyroidism with “superscan-like” hypermetabolic FDG PET/CT pattern. Clin Nucl Med 2015;40:888-889.
  6. Chan M, Schembri GP. Combined 18F-FDG PET/CT and 68Ga DOTATATE PET/CT “superscan” in metastatic pancreatic neuroendocrine tumor. Clin Nucl Med 2017;42:108-109.
  7. Tan TH, Wong TH, Hassan SZ, Lee BN. Unusual bone superscan, MIBG superscan, and 68Ga DOTATATE PET/CT in metastatic pheochromocytoma. Clin Nucl Med 2015;40:867-868.
  8. Agarwal KK, Tripathi M, Kumar R, Bal C. Metastatic superscan in prostate carcinoma on gallium-68-prostate-specific membrane antigen positron emission tomography/computed tomography scan. Indian J Nucl Med 2016;31:150-151.