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¹⁸F-FDG PET/CT Imaging of a Grade 3 Lymphomatoid Granulomatosis in an Immunocompromised Pediatric Patient

10.4274/mirt.galenos.2022.32848

• Selin Kesim
• Feyza Şen
• Salih Özgüven
• Tunç Öneş

Received Date: 29.09.2021 Accepted Date: 28.01.2022 Mol Imaging Radionucl Ther 2023;32(1):68-70 PMID: 36820008

• Abstract
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Lymphomatoid granulomatosis is a rare extranodal Epstein-Barr virus-driven B-cell lymphoproliferative disease, involving predominantly lung, less often skin, kidney, and central nervous system. Here, we present a pediatric case with primary immunodeficiency, diagnosed with pathologically proven pulmonary grade-III lymphomatoid granulomatosis. ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) imaging demonstrated ¹⁸F-FDG avid pulmonary masses with central air-bronchograms and cavitations. Although the definitive diagnosis depends on biopsy, ¹⁸F-FDG PET/CT serves as a complementary imaging tool to evaluate the extent of the disease and response to treatment.

Keywords: Lymphomatoid granulomatosis, pulmonary involvement, 18F-FDG PET/CT

Ethics

Informed Consent: We have obtained all appropriate patient consent forms. In the form the patient has given her consent for her images and other clinical information to be reported in the journal.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: S.K., F.Ş., S.Ö., T.Ö., Concept: S.K., F.Ş., Design: S.K., F.Ş., Data Collection or Processing: S.K., F.Ş., Analysis or Interpretation: S.K., F.Ş., Literature Search: S.K., F.Ş., Writing: S.K., F.Ş.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.

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