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11C-Methionine PET/CT and 18F-FDG PET/CT in the Evaluation of Adult Alveolar Rhabdomyosarcoma


  • Yuka Hiroshima
  • Yoichi Otomi
  • Takayoshi Shinya
  • Hideki Otsuka
  • Masafumi Harada

Received Date: 28.12.2021 Accepted Date: 20.02.2022 Mol Imaging Radionucl Ther 2023;32(1):62-64 PMID: 36819829

A 70-year-old man with a tumor in the nasal and paranasal space, was pathologically diagnosed with an alveolar rhabdomyosarcoma, with right cervical lymph node metastasis. Magnetic resonance imaging revealed a primary tumor in the nasal and paranasal sinuses, with associated intracranial infiltration. 11C-methionine positron emission tomography/computed tomography (PET/CT) revealed increased uptake in the primary tumor and right cervical lymph node metastasis. 18F-fluorodeoxyglucose PET/CT also revealed increased uptake in the primary tumor and right cervical lymph node. However, the physiological brain uptake overlapped with the primary tumor uptake. Our case suggests the usefulness of 11C-methionine PET/CT for accurately assessing the extent of alveolar rhabdomyosarcoma, especially in cases with intracranial infiltration or those approximating the brain.

Keywords: 11C-methionine, 18F-FDG, alveolar rhabdomyosarcoma, PET/CT


Informed Consent: Written informed consent was obtained from the patient.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Concept: Y.O., T.S., Design: Y.O., T.S., Data Collection or Processing: Y.H., Y.O., Analysis or interpretation: Y.O., T.S., H.O., M.H., Literature Search: Y.H., Y.O., Writing: Y.H.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.


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