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Isolated Castrate-resistant Prostate Cancer Metastasis to Both Adrenal Glands Detected on 68Ga PSMA PET/CT


  • Osman Kanatsız
  • Filiz Özülker
  • Tamer Aydın
  • Tamer Özülker

Received Date: 01.05.2022 Accepted Date: 15.02.2023 Mol Imaging Radionucl Ther 2023;32(3):244-246 PMID: 37870375

A 61-year-old male patient, who had undergone radical prostatectomy, underwent 68Ga labeled prostate-specific membrane antigen (PSMA) positron emission tomography/computerized tomography (PET/CT) for evaluation of suspected biochemical recurrence of prostate cancer (PCa). PET/CT scan showed increased 68Ga PSMA expressions in hypodense mass lesions in both adrenal gland localizations. An adrenal gland tru-cut biopsy was performed for the right side, which showed poor-differentiated carcinoma metastases associated with the patient’s high-grade PCa. As far as we could determine based on an extensive literature search, this is the second case in which isolated adrenal metastasis was detected by 68Ga PSMA PET/CT study in a patient with PCa.

Keywords: Prostate cancer, 68Ga PSMA PET/CT, adrenal metastasis


Informed Consent: Patient consent for the diagnostic study was obtained.

Peer-review: Internally peer-reviewed.

Authorship Contributions

Concept: O.K., F.Ö., Design: O.K., F.Ö., Data Collection or Processing: O.K., F.Ö., T.A., Analysis or Interpretation: O.K., F.Ö., T.A., T.Ö., Literature Search: O.K., F.Ö., T.Ö., Writing: O.K., F.Ö., T.Ö.

Conflict of Interest: No conflicts of interest were declared by the authors.

Financial Disclosure: The authors declare that this study has received no financial support.


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