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Short Latency Radiation Induced Osteosarcoma Detected on 18F-FDG PET/CT Scan in Solitary Plasmacytoma


  • Sana Munir Gill
  • Aamna Hassan
  • Namra Asghar
  • Usman Ahmad
  • Umm e Kalsoom Awan
  • Imran Khalid Niazi

Received Date: 08.06.2020 Accepted Date: 24.11.2020 Mol Imaging Radionucl Ther 2022;31(1):66-68 PMID: 35114756

18Fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) plays a pivotal role in the staging, restaging, and surveillance of various bone tumors, including plasmacytomas and osteosarcomas. Solitary plasmacytomas most frequently occur in the bones and are primarily treated with either surgery or radiotherapy. Radiation-induced osteosarcomas (RIOS) usually develop after a median interval of 11 years between radiation and sarcoma presentation. However, these can rarely present with a short latent period of 4 years or even lesser. In such cases, whole-body imaging plays a vital role in the early detection and management of RIOS. Herein, we present the case of a 29-year-old female patient with solitary plasmacytoma undergoing a follow-up whole-body 18F-FDG PET/CT, which revealed metastatic RIOS after a short latent period.

Keywords: Solitary plasmacytoma, 18F-FDG PET/CT, radiation-induced osteosarcoma


Informed Consent: IRB approval obtained.

Peer-review: Externally and internally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: A.H., U.A., U.K.A., I.K.N., Concept: S.M.G., A.H., Design: S.M.G., A.H., Data Collection or Processing: S.M.G., A.H., N.A., Analysis or Interpretation: S.M.G., A.H., N.A., I.K.N., U.A., U.K.A., Literature Search: S.M.G., A.H., Writing: S.M.G., A.H.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.


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