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Pneumonia with Intense ⁶⁸Ga-FAPI Uptake Mimicking Metastasis on ⁶⁸Ga-FAPI PET/CT in a Patient with Rectal Cancer

10.4274/mirt.galenos.2023.07830

• Özge Erol Fenercioğlu
• Ediz Beyhan
• Nilay Şengül Samancı
• Tevfik Fikret Çermik
• Nurhan Ergül

Received Date: 18.07.2022 Accepted Date: 04.02.2023 Mol Imaging Radionucl Ther 2023;32(3):237-238 PMID: 37870301

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A 70-year-old man with newly diagnosed rectum adenocarcinoma was referred to ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) for staging, and ⁶⁸Ga-fibroblast activation protein inhibitor (FAPI)-04 PET/CT for ongoing trial. Both ¹⁸F-FDG PET/CT and ⁶⁸Ga-FAPI-04 PET/CT showed intense uptake in the primary rectal tumor, and also in nodular areas in the right lung. Due to intense ⁶⁸Ga-FAPI-04 and ¹⁸F-FDG uptake, the lung lesions were considered as metastases. However the lesions were reduced in size on CT after 20 days antibiotherapy and diagnosed as pneumonia.

Keywords: 68Ga-FAPI, PET/CT, CT, pneumonia

Ethics

Informed Consent: Written informed consent was obtained from the participant.

Peer-review: Externally and internally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: Ö.E.F., E.B., N.Ş.S., T.F.Ç., N.E., Concept: Ö.E.F., E.B., N.Ş.S., T.F.Ç., N.E., Design: Ö.E.F., E.B., N.Ş.S., T.F.Ç., N.E., Data Collection or Processing: Ö.E.F., E.B., N.Ş.S., T.F.Ç., N.E., Analysis or Interpretation: Ö.E.F., E.B., N.Ş.S., T.F.Ç., N.E., Literature Search: Ö.E.F., E.B., N.Ş.S., T.F.Ç., N.E., Writing: Ö.E.F., E.B., N.Ş.S., T.F.Ç., N.E.

Conflict of Interest: No conflicts of interest were declared by the authors.

Financial Disclosure: The authors declare that this study has received no financial support.

Images

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