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PET/CT Imaging of Inflammatory Myofibroblastic Tumor of the Thigh


  • Refia Yükseltürk
  • Aslıhan Yıldırım
  • Nedim C. M. Gülaldı

Received Date: 14.10.2022 Accepted Date: 04.02.2023 Mol Imaging Radionucl Ther 2023;32(3):239-243 PMID: 37870374

A 13-year-old male patient presented with right leg pain and walking difficulty. Contrast-enhanced magnetic resonance imaging showed a softtissue lesion between muscle groups in the anterior half of the right thigh. The excisional biopsy result ended in an inflammatory myofibroblastic tumor (IMT). The 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) scan showed hypermetabolism in the multifocal soft tissue lesion and also confirmed that no other distant foci were present. A three-phase Tc-99m-methylene diphosphonate study of the region showed heterogeneously increased vascularity within the region. We described an unusual case of IMT in a pediatric patient and the importance of PET/CT scanning to delineate the lesion.

Keywords: Inflammatory myofibroblastic tumor, bone scan, magnetic resonance imaging, 18F-FDG PET/CT


Informed Consent: The patient consent was obtained.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Concept: N.C.M.G., Design: N.C.M.G., Data Collection or Processing: R.Y., A.Y., Analysis or Interpretation: R.Y., N.C.M.G., Literature Search: R.Y., A.Y., Writing: R.Y., N.C.M.G.

Conflict of Interest: No conflicts of interest were declared by the authors.

Financial Disclosure: The authors declare that this study has received no financial support.


  1. Savvidou OD, Sakellariou VI, Papakonstantinou O, Skarpidi E, Papagelopoulos PJ. Inflammatory myofibroblastic tumor of the thigh: presentation of a rare case and review of the literature. Case Rep Orthop 2015;2015:814241.
  2. Raad RA, Haddad L, Jabbour T, El-Rassi Z. Inflammatory Myofibroblastic Tumor of the Liver Mimicking Metastasis on 18F-FDG PET/CT. Clin Nucl Med 2021;46:47-48.
  3. Liu H, Yang X, Fan D, Lv T, Chen Y. Mesenteric Inflammatory Myofibroblastic Tumor on 68Ga-FAPI PET/CT. Clin Nucl Med 2021;46:1026-1027.
  4. Dalton BG, Thomas PG, Sharp NE, Manalang MA, Fisher JE, Moir CR, St Peter SD, Iqbal CW. Inflammatory myofibroblastic tumors in children. J Pediatr Surg 2016;51:541-544.
  5. Ma C, Lu J, Chen G, Wang W, Su F, Su X. Inflammatory myofibroblastic tumor mimicking lymphoma on 18F-FDG PET/CT. Report of a case and review of the literature. Hell J Nucl Med 2018;21:77-80.
  6. Dong A, Wang Y, Dong H, Gong J, Cheng C, Zuo C, Lu J. Inflammatory myofibroblastic tumor: FDG PET/CT findings with pathologic correlation. Clin Nucl Med 2014;39:113-121.
  7. Jiang JY, Comsa M, Wong VCK, Mansberg R. Steroid responsive inflammatory myofibroblastic tumor of the lung evaluated by FDG PET/CT imaging. Radiol Case Rep 2022;17:907-910.