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Increased Bone Marrow 18F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia


  • Luca Filippi

Received Date: 09.08.2019 Accepted Date: 30.09.2019 Mol Imaging Radionucl Ther 2020;29(1):45-48 PMID: 32079389

A 57-year-old male with history of thalassemia intermedia and hepatocellular carcinoma underwent a positron emission tomography/computed tomography (PET/CT) scan with 18F-choline before radioembolization procedure with 90Y-microspheres. The PET/CT scan with 18F-choline demonstrated highly increased tracer incorporation within a gross lesion in the hepatic dome coupled with diffuse activity in bone marrow, this latter aspect was probably due to the compensatory hematopoiesis stimulation induced by chronic hemolysis. This pattern of skeletal 18F-choline uptake should be considered as a peculiar PET/CT finding in thalassemic patients.

Keywords: 18F-choline, positron emission tomography/computed tomography, hepatocellular carcinoma, thalassemia


Informed Consent: This article does not contain any studies with human participants or animals performed by any of the authors.

Peer-review: Externally and internally peer-reviewed.

Financial Disclosure: The author declared that this study received no financial support.


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