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Multiple Subcutaneous 18F-FDG-avid Granulomas Due to Enoxaparin Injection


  • Özge Erol Fenercioğlu
  • Nurhan Ergül
  • Ediz Beyhan
  • Rahime Şahin
  • Tevfik Fikret Çermik

Received Date: 07.10.2020 Accepted Date: 15.02.2021 Mol Imaging Radionucl Ther 2022;31(2):157-159 PMID: 35771074

A 67-year-old female patient with metastatic gastric adenocarcinoma was referred to 18fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for restaging. PET/CT revealed liver metastasis and the patient received six-cycles of chemotherapy. On control 18F-FDG PET/CT the liver lesion disappeared but newly formed multiple foci of increased uptake in the subcutaneous adipose tissues of the abdominal wall were detected. The uptake was related to nodular lesions resulting from an idiosyncratic reaction to enoxaparin and from local trauma through repeated injections.

Keywords: Enoxaparin, granuloma, 18F-FDG PET/CT


Informed Consent: The written and verbal consent has been received before the PET/CT scan.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: Ö.E.F., N.E., E.B., R.Ş., T.F.Ç., Concept: Ö.E.F., N.E., E.B., R.Ş., T.F.Ç., Design: Ö.E.F., N.E., E.B., R.Ş., T.F.Ç., Data Collection or Processing: Ö.E.F., N.E., E.B., R.Ş., T.F.Ç., Analysis or Interpretation: Ö.E.F., N.E., E.B., R.Ş., T.F.Ç., Literature Search: Ö.E.F., N.E., E.B., R.Ş., T.F.Ç., Writing: Ö.E.F., N.E., E.B., R.Ş., T.F.Ç.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.


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