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Metabolic Activity of Neurogenic Heterotopic Ossification on 18F-FDG PET/CT Matching with Ongoing Osteoblastic Activity on Bone Scan


  • Matthieu Dietz
  • Jeremie Tordo

Received Date: 29.12.2020 Accepted Date: 10.04.2021 Mol Imaging Radionucl Ther 2022;31(2):166-168 PMID: 35771089

A 54-year-old man, with previous history of neurogenic heterotopic ossification (HO) in muscles around the left hip following a spinal cord injury ten months earlier, was referred to our nuclear medicine center for an 18fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) to rule out a spondylodiscitis. No sign of spondylodiscitis was found on 18F-FDG PET/CT, but images revealed an increased 18F-FDG uptake in HO areas, matching with ongoing osteoblastic activity on a following bone scan.

Keywords: Heterotopic ossification, bone scan, 18F-FDG PET/CT


Informed Consent: A written informed consent was obtained.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Concept: J.T., Design: J.T., Data Collection or Processing: M.D., J.T., Analysis or Interpretation: M.D., J.T., Literature Search: M.D., Writing: M.D., J.T.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.


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