Interesting Image

Lymphoblastic Involvement of the Bone Marrow as a Cause of Superscan Appearance in 18F-Fluorodeoxyglucose Positron Emission Tomography/ Computed Tomography


  • Zehra Pınar Koç
  • Pelin Özcan Kara
  • Aydan Akdeniz
  • Mehmet Yaldız

Received Date: 07.02.2019 Accepted Date: 05.11.2019 Mol Imaging Radionucl Ther 2020;29(2):85-87 PMID: 32368881

The 18F-fluorodeoxylucose (FDG) positron emission tomography (PET) is the gold standard imaging modality in the staging of lymphoma. The superscan appearance in the FDG PET/computerized tomography (CT) imaging might be because of benign diseases or malignant infiltrations. This case report presents lymphomatous blastic infiltration as a cause of superscan appearance in 18F-FDG PET/CT.

Keywords: Superscan, FDG, PET/CT, lymphoma


Informed Consent: Consent form was filled out by all participants.

Peer-review: Externally and internally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: Z.P.K., P.Ö.K., A.A., M.Y., Concept: Z.P.K., P.Ö.K., Design: Z.P.K., P.Ö.K., Data Collection or Processing: Z.P.K., P.Ö.K., A.A., M.Y., Analysis or Interpretation: Z.P.K., P.Ö.K., Literature Search: Z.P.K., P.Ö.K., Writing: Z.P.K., P.Ö.K., A.A., M.Y.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.


  1. Manov JJ, Roth PJ, Kuker R. Clinical Pearls: Etiologies of Superscan Appearance on Fluorine-18-Fludeoxyglucose Positron Emission Tomography-Computed Tomography. Indian J Nucl Med 2017;32:259-265.
  2. Kaneko K, Nishie A, Arima F, Yoshida T, Ono K, Omagari J, Honda H. A case of diffuse-type primary hepatic lymphoma mimicking diffuse hepatocellular carcinoma. Ann Nucl Med 2011;25:303-307.
  3. Oe A, Habu D, Kawabe J, Torii K, Kawamura E, Kotani J, Hayashi T, Sakaguchi H, Shiomi S. A case of diffuse hepatic angiosarcoma diagnosed by FDG-PET. Ann Nucl Med 2005;19:519-521.
  4. Taneja S, Achong DM. Hepatic superscan on PET/CT due to Richter’s transformation of chronic lymphocytic leukemia. Clin Nucl Med 2010;35:644-645.
  5. Yang G, Nie P, Wang Z, Xing X. (18)F-FDG hepatic superscan caused by a non-germinal center subtype of diffuse large B-cell lymphoma. Eur J Nucl Med Mol Imaging 2016;43:1928.
  6. Parida GK, Soundararajan R, Passah A, Bal C, Kumar R. Metabolic Skeletal Superscan on 18F-FDG PET/CT in a Case of Acute Lymphoblastic Leukemia. Clin Nucl Med 2015;40:567-568.