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Findings of I-131 SPECT/CT, 18F-FDG, and 68Ga-FAPI-04 PET/CT Imaging in a Patient Treated with Radioiodine Therapy for Metastatic Papillary Thyroid Carcinoma


  • Gamze Tatar
  • Göksel Alçın
  • Özge Erol Fenercioğlu
  • Rahime Şahin
  • Tevfik Fikret Çermik

Received Date: 26.01.2022 Accepted Date: 20.07.2022 Mol Imaging Radionucl Ther 2023;32(1):57-61 PMID: 36819619

A 50-year-old man undergone total thyroidectomy and histopathology revealed papillary thyroid carcinoma with a tumor size of 4.5 cm. The patient was referred to a nuclear medicine clinic for radioiodine therapy. Since the thyroglobulin level before the treatment was 495 ug/L, low-dose (185 MBq) I-131 scan was performed. In addition to multiple liver metastases, bone metastases were detected in the sacrum and right 7th rib in I-131 whole body scanning and single photon emission computed tomography/computed tomography (CT) imaging at the time of initial staging. We present a case of multiple metastatic papillary thyroid carcinoma whose radioiodine treatment response and clinical outcome were evaluated with 18F-fluorodeoxyglucose and Gallium-68 FAPI-04 positron emission tomography/CT.

Keywords: Papillary thyroid carcinoma, liver metastasis, radioiodine therapy, I-131, 18F-FDG, 68Ga FAPI-04, PET/CT


Informed Consent: The patient gave written informed consent for imaging modalities and permitted publication of his medical data.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: G.T., Ö.E.F., R.Ş., T.F.Ç., Concept: G.T., G.A., T.F.Ç., Design: G.T., G.A., T.F.Ç., Data Collection or Processing: G.T., Ö.E.F., R.Ş., Analysis or Interpretation: G.T., G.A., T.F.Ç., Literature Search: G.T., Writing: G.T., T.F.Ç.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.


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