Interesting Image

Detection of Rare Gallbladder Microperforation by 18F-FDG PET/CT in a Patient with Maxillary Sinus Cancer


  • Zehranur Tosunoğlu
  • Selim Doğan
  • Ceyda Turan Bektaş
  • Tevfik Fikret Çermik
  • Esra Arslan

Received Date: 08.04.2023 Accepted Date: 14.07.2023 Mol Imaging Radionucl Ther 2024;33(1):47-49 PMID: 38390789

Gallbladder perforation is one of the most serious complications of cholecystitis and is rarely seen in 2-11% of cases. Pericholecystic abscesses secondary to gallbladder perforation are rare. Rapid diagnosis is important because of high morbidity and mortalityrates. A subcapsular abscess secondary to gallbladder microperforation is presented on 18F-fluorodeoxyglucose positron emission tomography/computed tomography performed for restaging in a patient with maxillary sinus cancer.

Keywords: Gallbladder micro-perforation, abscess, 18F-FDG PET/CT


Informed Consent: The patient consent was obtained.

Authorship Contributions

Surgical and Medical Practices: Z.T., S.D., C.T.B., T.F.Ç., E.A., Concept: Z.T., S.D., C.T.B., E.A., T.F.Ç., Design: Z.T., C.T.B., S.D., T.F.Ç., E.A., Data Collection or Processing: Z.T., S.D., C.T.B., T.F.Ç., E.A., Analysis or Interpretation: S.D., C.T.B., T.F.Ç., E.A., Z.T., Literature Search: Z.T., S.D., C.T.B., T.F.Ç., E.A., Writing: Z.T., T.F.Ç., E.A., S.D., C.T.B.

Conflict of Interest: No conflicts of interest were declared by the authors.

Financial Disclosure: The authors declare that this study has received no financial support.


  1. Kochar K, Vallance K, Mathew G, Jadhav V. Intrahepatic perforation of the gall bladder presenting as liver abscess: case report, review of literature and Niemeier’s classification. Eur J Gastroenterol Hepatol 2008;20:240-244.
  2. Kim PN, Lee KS, Kim IY, Bae WK, Lee BH. Gallbladder perforation: comparison of US findings with CT. Abdom Imaging 1994;19:239-242.
  3. Quiroga-Garza A, Alvarez-Villalobos NA, Angeles-Mar HJ, Garcia-Campa M, Muñoz-Leija MA, Salinas-Alvarez Y, Elizondo-Omaña RE, Guzmán-López S. Localized gallbladder perforation: a systematic review of treatment and prognosis. HPB (Oxford) 2021;23:1639-1646.
  4. Smith EA, Dillman JR, Elsayes KM, Menias CO, Bude RO. Cross-sectional imaging of acute and chronic gallbladder inflammatory disease. AJR Am J Roentgenol 2009;192:188-196.
  5. Peer A, Witz E, Manor H, Strauss S. Intrahepatic abscess due to gallbladder perforation. Abdom Imaging 1995;20:452-455.
  6. Singh K, Singh A, Vidyarthi SH, Jindal S, Thounaojam CK. Spontaneous intrahepatic type II gallbladder perforation: a rare cause of liver abscess - case report. J Clin Diagn Res 2013;7:2012-2014.
  7. Pijl JP, Nienhuis PH, Kwee TC, Glaudemans AWJM, Slart RHJA, Gormsen LC. Limitations and pitfalls of FDG-PET/CT in infection and inflammation. Semin Nucl Med 2021;51:633-645.
  8. Tan GJ, Berlangieri SU, Lee ST, Scott AM. FDG PET/CT in the liver: lesions mimicking malignancies. Abdom Imaging 2014;39:187-195.
  9. Rahman WT, Wale DJ, Viglianti BL, Townsend DM, Manganaro MS, Gross MD, Wong KK, Rubello D. The impact of infection and inflammation in oncologic 18F-FDG PET/CT imaging. Biomed Pharmacother 2019;117:109168.