Interesting Image

COVID-19 Pneumonia was Incidentally Detected on 18F-Fluorocholine PET/CT in a Work-up for Prostate Cancer

10.4274/mirt.galenos.2021.19480

  • Omar Ait Sahel
  • Yassir Benameur
  • Salah Oueriagli Nabih
  • Abderrahim Doudouh

Received Date: 11.06.2021 Accepted Date: 06.07.2021 Mol Imaging Radionucl Ther 2022;31(3):231-233 PMID: 36268898

This is a presentation of the case of a patient who underwent 18F-fluorocholine positron emission/computed tomography to stage a prostate cancer with incidentally found bilateral pneumonia. A high prevalence of incidental pneumonia is very probable under the current circumstance of coronavirus disease-2019 (COVID-19) pandemic, and oncological patients are at increased risk of COVID-19 with poorer outcome. The lung inflammatory burden in the case of COVID-19 infection can be demonstrated by 18F-fluorocholine.

Keywords: COVID-19, pneumonia, prostate cancer, 18F-fluorocholine, PET/CT

Ethics

Informed Consent: Written informed consent of the patient was obtained.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: O.A.S., A.D., Concept: O.A.S., A.D., Design: O.A.S., A.D., Data Collection or Processing: O.A.S., Y.B., Analysis or Interpretation: O.A.S., Y.B., S.O.N., Literature Search: O.A.S., S.O.N., Writing: O.A.S.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.

Images

  1. Dai M, Liu D, Liu M, Zhou F, Li G, Chen Z, Zhang Z, You H, Wu M, Zheng Q, Xiong Y, Xiong H, Wang C, Chen C, Xiong F, Zhang Y, Peng Y, Ge S, Zhen B, Yu T, Wang L, Wang H, Liu Y, Chen Y, Mei J, Gao X, Li Z, Gan L, He C, Li Z, Shi Y, Qi Y, Yang J, Tenen DG, Chai L, Mucci LA, Santillana M, Cai H. Patients with cancer appear more vulnerable to SARS-CoV-2: a multicenter study during the COVID-19 outbreak. Cancer Discov 2020;10:783-791.
  2. Scarlattei M, Baldari G, Silva M, Bola S, Sammartano A, Migliari S, Graziani T, Cidda C, Sverzellati N, Ruffini L. Unknown SARS-CoV-2 pneumonia detected by PET/CT in patients with cancer. Tumori Journal 2020;106:325-332.
  3. Minamimoto R, Hotta M, Ishikane M, Inagaki T. FDG-PET/CT images of COVID-19: a comprehensive review. Glob Health Med 2020;2:221-226.
  4. Olivari L, Riccardi N, Rodari P, Angheben A, Artioli P, Salgarello M. COVID-19 pneumonia: increased choline uptake with 18F-choline PET/CT. Eur J Nucl Med Mol Imaging 2020;47:2476-2477.
  5. García Vicente AM, Soriano Castrejón Á. Incidental COVID-19 pneumonia on 18F-fluorocholine PET/CT. Clin Nucl Med 2020;45:e376-e377.
  6. Savelli G, Bonacina M, Rizzo A, Zaniboni A. Activated macrophages are the main inflammatory cell in COVID-19 interstitial pneumonia infiltrates. Is it possible to show their metabolic activity and thus the grade of inflammatory burden with 18F-fluorocholine PET/CT? Med Hypothese 2020;144:109885.
  7. Wyss MT, Weber B, Honer M, Späth N, Ametamey SM, Westera G, Bode B, Kaim AH, Buck A. 18F-choline in experimental soft tissue infection assessed with autoradiography and high-resolution PET. Eur J Nucl Med Mol Imaging 2004;31:312-316.