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Atypical Presentation of Metastatic Castrate-resistant Prostate Cancer in a Middle Aged African Male with Good Response to Radioligand Therapy


  • Osayande Evbuomwan
  • Walter Endres
  • Tebatso Tebeila
  • Gerrit Engelbrecht

Received Date: 12.04.2023 Accepted Date: 15.10.2023 Mol Imaging Radionucl Ther 2024;33(1):57-62 PMID: 38390823

Prostate cancer typically follows a characteristic pattern of metastatic spread to the pelvic lymph nodes and bone. Atypical patterns of metastasis are rare but have been documented. In African men, this disease tends to follow a more aggressive course, with the possibility of an atypical site of metastatic spread. We present a case of a 58-year- old African male with metastatic castrate-resistant prostate cancer who presented with both typical and atypical patterns of metastatic disease detected by a fluorine 18 prostate-specific membrane antigen positron emission tomography/computed tomography scan. This patient also had a good response to radioligand therapy.

Keywords: Metastatic castrate-resistant prostate cancer, atypical metastases, 18F-PSMA


Informed Consent: Informed consent was obtained from the patient.

Authorship Contributions

Surgical and Medical Practices: O.E., Concept: O.E., G.E., Design: O.E., W.E., T.T., Data Collection or Processing: O.E., W.E., T.T., Analysis or Interpretation: O.E., W.E., T.T., G.E., Literature Search: O.E., Writing: O.E.

Conflict of Interest: No conflicts of interest were declared by the authors.

Financial Disclosure: The authors declare that this study has received no financial support.


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