Neurolymphomatosis: The Sinister Face of Lymphoma
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VOLUME: 34 ISSUE: 2
P: 156 - 158
June 2025

Neurolymphomatosis: The Sinister Face of Lymphoma

Mol Imaging Radionucl Ther 2025;34(2):156-158
1. Shaukat Khanum Memorial Cancer Hospital and Research Centre, Clinic of Nuclear Medicine, Lahore, Pakistan
2. Landspítali -The National University Hospital, Clinic of Nuclear Medicine, Reykjavik, Iceland
3. East Kent Hospitals University NHS Foundation Trust, Department of Nuclear Medicine, Canterbury, United Kingdom
No information available.
No information available
Received Date: 20.08.2024
Accepted Date: 23.12.2024
Online Date: 03.06.2025
Publish Date: 03.06.2025
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Abstract

Neurolymphomatosis (NL) is a rare clinical condition characterized by the infiltration of malignant lymphocytes into the cranial or peripheral nerves, nerve roots, or plexus. Diagnosis can be clinically challenging due to its variable presentation. It usually occurs in B cell lymphoma; however, a few cases of extranodal killer/T cell lymphoma. Most cases present at a secondary site in patients with primary site in remission. 18Fluorine fluorodeoxyglucose positron emission tomography/computed tomography plays an important role in the early detection of NL, resulting in timely treatment. We present a case of a 24-year-old male with nasal natural killer T cell lymphoma who initially responded to treatment but relapsed with NL based on clinical and radiological findings.

Keywords:
Neurolymphomatosis, natural killer T cell lymphoma, 18Fluorine fluorodeoxyglucose positron emission tomography/computed tomography, lymphom

Ethics

Informed Consent: An informed consent was obtained from the patient.
Authorship Contributions: Concept: S.M.G., P.A.A.A.Q., Design: S.M.G., A.H., P.A.A.A.Q., H.B., Data Collection or Processing: S.M.G., P.A.A.A.Q., Analysis or Interpretation: S.M.G., A.H., P.A.A.A.Q., H.B., Literature Search: S.M.G., Writing: S.M.G., A.H., P.A.A.A.Q.
Conflict of Interest: No conflicts of interest were declared by the authors.
Financial Disclosure: The authors declare that this study has received no financial support.

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