Abstract
A 68-year-old woman with low back pain for 2 months was admitted. T2-weighted fat-saturated imaging revealed hyperintense lesions in multiple lumbar regions, suggesting the possibility of bone metastases. Multiple osteolytic and mixed osteolytic-osteoblastic lesions with significant 18F-fluorodeoxyglucose (18F-FDG) uptake, as well as multiple osteoblastic lesions with mild 18F-FDG uptake, were observed on subsequent 18F-FDG positron emission tomography/computed tomography without an identifiable primary lesion. This patient was pathologically diagnosed with low-grade myofibroblastic sarcoma (LGMS) after biopsy and surgery. Although multiple bone involvement in LGMS is extremely rare, this case suggests that it should be considered in the differential diagnosis of multiple bone metastases.
Keywords:
Low-grade myofibroblastic sarcoma, bone destruction, 18F-FDG PET/CT
Ethics
Informed Consent: The written informed consent has been obtained from the patient.
Authorship Contributions
Concept: L.S., W.Z., Design: L.S., W.Z., Data Collection or Processing: X.H., Analysis or Interpretation: X.H., Literature Search: H.L., N.G., Writing: H.L.
Conflict of Interest: No conflicts of interest were declared by the authors.
Financial Disclosure: This work was supported by the Key Clinical Projects of Peking University Third Hospital (no.: BYSY2022060).
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