Multiple Bone Involvement in Low-grade Myofibroblastic Sarcoma Demonstrated on <sup>18</sup>F-FDG PET/CT
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P: 206-208
October 2024

Multiple Bone Involvement in Low-grade Myofibroblastic Sarcoma Demonstrated on 18F-FDG PET/CT

Mol Imaging Radionucl Ther 2024;33(3):206-208
1. Peking University Third Hospital Department of Nuclear Medicine, Beijing, China
No information available.
No information available
Received Date: 26.09.2023
Accepted Date: 25.03.2024
Online Date: 07.10.2024
Publish Date: 07.10.2024
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Abstract

A 68-year-old woman with low back pain for 2 months was admitted. T2-weighted fat-saturated imaging revealed hyperintense lesions in multiple lumbar regions, suggesting the possibility of bone metastases. Multiple osteolytic and mixed osteolytic-osteoblastic lesions with significant 18F-fluorodeoxyglucose (18F-FDG) uptake, as well as multiple osteoblastic lesions with mild 18F-FDG uptake, were observed on subsequent 18F-FDG positron emission tomography/computed tomography without an identifiable primary lesion. This patient was pathologically diagnosed with low-grade myofibroblastic sarcoma (LGMS) after biopsy and surgery. Although multiple bone involvement in LGMS is extremely rare, this case suggests that it should be considered in the differential diagnosis of multiple bone metastases.

Keywords:
Low-grade myofibroblastic sarcoma, bone destruction, 18F-FDG PET/CT

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