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68Ga PSMA Uptake at Roux-en-Y Eso-jejunostomy Junction Mimicking the Recurrence of Gastric Carcinoma in PET/CT

10.4274/mirt.galenos.2020.86729

  • Esra Arslan
  • Tamer Aksoy
  • Merve Cin
  • Coşkun Çakır
  • Fadime Didem Can Trabulus
  • Tevfik Fikret Çermik

Received Date: 10.11.2019 Accepted Date: 02.04.2020 Mol Imaging Radionucl Ther 2021;30(1):63-66

A 67-year-old male patient had undergone total gastrectomy and Roux-en-Y eso-jejunostomy 3 years ago for the treatment of tubular adenocarcinoma located at the corpus of the stomach. The patient was diagnosed with Gleason score 8 (4+4) metastatic prostate cancer during the follow-up period and received hormone therapy. Owing to his elevated prostate-specific antigen levels (77 ng/mL), his clinician referred him gallium-68 (68Ga) prostate-specific membrane antigen 11 (PSMA) positron emission tomography/computed tomography (PET/CT) for restaging. PET/CT showed multiple 68Ga PSMA receptor-positive skeletal lesions and linear PSMA activity at the eso-jejunostomy junction. He was then referred to undergo 18fluorine-fluorodeoxyglucose (18F-FDG) PET/CT to screen for gastric carcinoma recurrence. PET/CT images demonstrated no 18F-FDG avid lesion. However, endoscopy and biopsy performed with samples from the eso-jejunostomy junction revealed superficial benign squamous epithelial fragments.

Keywords: 68Ga-PSMA, 18F-FDG, PET/CT, gastric carcinoma, prostate carcinoma

Ethics

Informed Consent: The patient was asked for the verbal or written consent for the use of the individual clinical findings for research purposes.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: C.Ç., F.D.C.T, M.C., Concept: E.A., T.F.Ç., Design: E.A., T.F.Ç., T.A., Data Collection or Processing: E.A., T.F.Ç., T.A., Analysis or Interpretation: E.A., T.F.Ç., T.A, C.Ç., F.D.C.T, M.C., Literature Search: E.A., T.F.Ç., T.A., Writing: E.A., T.F.Ç., T.A.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.

Images

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