Interesting Image

¹⁸F-FDG PET/CT Imaging in an Unusual Case of Cutaneous Melanoma Arising From Congenital Melanocytic Nevus in a Two-year-old Girl

10.4274/mirt.galenos.2020.48278

• Seval Erhamamcı
• Mehmet Reyhan
• Nebil Bal
• Neşe Torun
• Ali Fuat Yapar

Received Date: 22.04.2020 Accepted Date: 31.05.2020 Mol Imaging Radionucl Ther 2021;30(2):119-121 PMID: 34082516

• Abstract
• Full Text
• Video - Image
• References
• 9
• 1002

Childhood malignant melanoma (MM) is extremely uncommon. We report an unusual case of cutaneous melanoma that developed from a medium-sized congenital melanocytic nevus (CMN) in a two-year-old girl. The patient had a history of CMN on the right hip, and she presented with a new ulcerative area with irregular borders and bleeding on CMN. Histopathological examination of the nevus revealed a MM. ¹⁸Florfluorodeoxyglucose (¹⁸F-FDG) positron emission tomography/computed tomography was performed for metastatic evaluation. The scan demonstrated metastatic increased ¹⁸F-FDG uptake in the right external iliac and inguinal lymph nodes.

Keywords: 18F-FDG PET/CT, childhood, cutaneous melanoma, congenital melanocytic nevus

Ethics

Informed Consent: Waived.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Concept: S.E., Design: S.E., Data Collection or Processing: S.E., M.R., N.B., N.T., A.F.Y., Analysis or Interpretation: S.E., M.R., N.B., N.T., A.F.Y., Literature Search: S.E., Writing: S.E.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.

Images

1. Han D, Zager JS, Han G, Marzban SS, Puleo CA, Sarnaik AA, Reed D, Messina JL, Sondak VK. The unique clinical characteristics of melanoma diagnosed in children. Ann Surg Oncol 2012;19:3888-3895.
2. Schaffer JV. Update on melanocytic nevi in children. Clin Dermatol 2015;33:368-386.
3. Veit-Haibach P, Vogt FM, Jablonka R, Kuehl H, Bockisch A, Beyer T, Dahmen G, Rosenbaum S, Antoch G. Diagnostic accuracy of contrast-enhanced FDG-PET/CT in primary staging of cutaneous malignant melanoma. Eur J Nucl Med Mol Imaging 2009;36:910-918.