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Incidental Spleen Cyst Mimicking Thyroid Carcinoma Metastasis: False-positive Uptake on Radioiodine Whole Body Scan

10.4274/mirt.galenos.2023.24992

• Mustafa Genç
• Nazım Coşkun
• Seyda Türkölmez

Received Date: 29.11.2022 Accepted Date: 08.01.2023 Mol Imaging Radionucl Ther 2023;32(2):175-177 PMID: 37337876

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In differentiated thyroid cancer, radioiodine therapy and whole body scans (WBS) are integral part of disease management. We present the case of a 33-year-old woman with multifocal thyroid carcinoma who was treated with radioiodine. Post-treatment WBS scintigraphy showed focal increased I-131 uptake in the spleen, although stimulated thyroglobulin level was not suggestive of distant metastasis. Dynamic magnetic resonance imaging performed later revealed that the finding was an incidental splenic cyst. Radioiodine uptake is not specific to the thyroid tissue. Benign pathologies showing increased radioiodine uptake should be considered in cases with splenic radioiodine accumulation in WBSs.

Keywords: Radioiodine therapy, thyroid cancer, spleen pathologies, whole body scan

Ethics

Informed Consent: All appropriate patient consent forms were obtained. In this form, the patient gave consent for their pictures and other clinical information to be reported in the journal.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: M.G., N.C., S.T., Concept: M.G., N.C., S.T., Design: M.G., N.C., S.T., Data Collection or Processing: M.G., N.C., S.T., Analysis or interpretation: M.G., N.C., S.T., Literature Search: M.G., N.C., S.T., Writing: M.G., N.C., S.T.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.

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