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Incidental Skeletal Findings on Sodium-fluoride Positron Emission Tomography: A Collection of Benign Tumors


  • Nada Almenieir
  • Marc Hickeson
  • Javier Novales-Diaz
  • Vilma Derbekyan
  • Gad Abikhzer

Received Date: 07.12.2019 Accepted Date: 26.04.2020 Mol Imaging Radionucl Ther 2021;30(2):113-116 PMID: 34082514

Sodium-fluoride (NaF) positron emission tomography (PET) is a sensitive method to detect altered bone mineralization. Its increasing use in routine clinical practice for metastatic bone disease has also resulted in the detection or characterization of incidental benign bone lesions. A spectrum of NaF PET scan cases with benign bone tumors are presented in this article, including whole body PET bone scan and selected PET/computed tomography (CT), CT, or magnetic resonance imaging (MRI) of the region of interest. The reader will be able to improve their knowledge related to the clinical presentation of these entities, some are rare and recognize based on NaF PET and CT/MRI patterns by reviewing these cases.

Keywords: NaF, sodium-fluoride PET, benign bone lesions


Informed Consent: Informed consent was waived.

Peer-review: Externally and internally peer-reviewed.

Authorship Contributions

Concept: N.A., G.A., Design: N.A., G.A., Data Collection or Processing: N.A., G.A., Analysis or Interpretation: N.A., M.H., J.N.D., V.D., G.A., Literature Search: N.A., Writing: N.A.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.

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