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A Case of Hypertrophic Pulmonary Osteoarthropathy in Both Upper and Lower Extremities: A Rare Involvement


  • Berna Okudan
  • Nazım Coşkun
  • Pelin Arıcan
  • Rıza Şefizade
  • Seniha Naldöken

Received Date: 21.06.2017 Accepted Date: 06.03.2018 Mol Imaging Radionucl Ther 2018;27(2):88-90 PMID: 29889032

Hypertrophic pulmonary osteoarthropathy (HPOA) is a paraneoplastic manifestation of gastric and, more frequently, lung carcinomas. It is characterized by extremity pain, clubbing, arthritis and periostitis of the long bones. Periostitis is the hallmark of HPOA and can be revealed with bone scintigraphy. Whole-body bone scintigraphy (WBBS) is very sensitive during the active lesion period and WBBS findings usually precede that of plain radiography. WBBS can also show improvement in the first 6 months following treatment, thus making it an important technique in the management and follow-up of these patients. While HPOA findings are usually seen in the lower extremities, involvement of both upper and lower extremities is a rare condition. In this case report, it is aimed to present findings of a 67-year-old male patient with lung cancer and complaint of extremity pain. We report on this patient to draw attention to HPOA of both upper and lower extremities.

Keywords: Hypertrophic pulmonary osteoarthropathy, lung cancer, upper extremity


Informed Consent: Consent form was filled out by all participants.

Peer-review: Externally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: B.O., N.C., P.A., R.Ş., S.N., Concept: B.O., N.C., P.A., R.Ş., S.N., Design: B.O., N.C., P.A., R.Ş., S.N., Data Collection or Processing: B.O., N.C., P.A., R.Ş., S.N., Analysis or Interpretation: B.O., N.C., P.A., R.Ş., S.N., Literature Search: B.O., N.C., P.A., R.Ş., S.N., Writing: B.O., N.C., P.A., R.Ş., S.N.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.


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