A 73-year-old woman with known diagnosis of chronic hepatitis B infection referred for 18F-fluorodeoxyglucose positron emission tomography/ computed tomography (18F-FDG PET/CT) and magnetic resonance imaging (MRI) after detection of a liver mass with 9 cm diameter in contrast enhanced CT. However, 18F-FDG PET/CT and MRI revealed diffuse infiltrating hepatocellular carcinoma lesions other than previously defined mass. After 9 months of Sorafenib treatment serum alpha feto protein levels dropped from 60,500 ng/mL to 801 ng/mL. Later 18F-FDG PET/MRI was performed for evaluation of response to treatment and revealed marked response to treatment.
Keywords: Hepatocellular carcinoma, positron emission tomography, fluorodeoxyglucose, magnetic resonance imaging, sorafenib
